Implications of phosphoinositide 3-kinase-Akt (PI3K-Akt) pathway in the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …
and mortality in aged population. Several transcription molecules, pathways, and molecular …
Nicotinic ACh receptors as therapeutic targets in CNS disorders
KT Dineley, AA Pandya, JL Yakel - Trends in pharmacological sciences, 2015 - cell.com
The neurotransmitter acetylcholine (ACh) can regulate neuronal excitability by acting on the
cys-loop cation-conducting ligand-gated nicotinic ACh receptor (nAChR) channels. These …
cys-loop cation-conducting ligand-gated nicotinic ACh receptor (nAChR) channels. These …
Neural stem cell differentiation into mature neurons: mechanisms of regulation and biotechnological applications
MS Vieira, AK Santos, R Vasconcellos… - Biotechnology …, 2018 - Elsevier
The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …
possibilities of applications in cell-based therapies such as tissue recomposition in …
Regulation of neurogenesis by calcium signaling
AB Toth, AK Shum, M Prakriya - Cell calcium, 2016 - Elsevier
Abstract Calcium (Ca 2+) signaling has essential roles in the development of the nervous
system from neural induction to the proliferation, migration, and differentiation of neural cells …
system from neural induction to the proliferation, migration, and differentiation of neural cells …
Human adult stem cells from diverse origins: an overview from multiparametric immunophenotyping to clinical applications
BR Sousa, RC Parreira, EA Fonseca… - Cytometry Part …, 2014 - Wiley Online Library
Stem cells are known for their capacity to self‐renew and differentiate into at least one
specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone …
specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone …
The association between prenatal exposure to phthalates and cognition and neurobehavior of children-evidence from birth cohorts
Q Zhang, XZ Chen, X Huang, M Wang, J Wu - Neurotoxicology, 2019 - Elsevier
Background Phthalate have been detected widely in the environment; while several studies
have indicated that prenatal phthalate exposure has adverse effects on neurodevelopment …
have indicated that prenatal phthalate exposure has adverse effects on neurodevelopment …
Developmental neurotoxicity of ortho-phthalate diesters: review of human and experimental evidence
A Miodovnik, A Edwards, DC Bellinger, R Hauser - Neurotoxicology, 2014 - Elsevier
Ortho-phthalate diesters, or phthalates, are widely used synthetic chemicals found primarily
in consumer products and polyvinyl chloride plastics. Experimental evidence suggests that …
in consumer products and polyvinyl chloride plastics. Experimental evidence suggests that …
Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells
A Somasundaram, AK Shum, HJ McBride… - Journal of …, 2014 - Soc Neuroscience
Calcium signals regulate many critical processes during vertebrate brain development
including neurogenesis, neurotransmitter specification, and axonal outgrowth. However, the …
including neurogenesis, neurotransmitter specification, and axonal outgrowth. However, the …
The role of G protein-coupled receptors (GPCRs) and calcium signaling in schizophrenia. Focus on GPCRs activated by neurotransmitters and chemokines
T Boczek, J Mackiewicz, M Sobolczyk, J Wawrzyniak… - Cells, 2021 - mdpi.com
Schizophrenia is a common debilitating disease characterized by continuous or relapsing
episodes of psychosis. Although the molecular mechanisms underlying this psychiatric …
episodes of psychosis. Although the molecular mechanisms underlying this psychiatric …
Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering
FMP Tonelli, AK Santos, KN Gomes… - International journal …, 2012 - Taylor & Francis
In recent years, significant progress has been made in organ transplantation, surgical
reconstruction, and the use of artificial prostheses to treat the loss or failure of an organ or …
reconstruction, and the use of artificial prostheses to treat the loss or failure of an organ or …