[HTML][HTML] Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management

S Pati, W Irfan, A Jameel, S Ahmed, RK Shahid - Cancers, 2023 - mdpi.com
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …

[HTML][HTML] Global impacts of western diet and its effects on metabolism and health: A narrative review

VJ Clemente-Suárez, AI Beltrán-Velasco… - Nutrients, 2023 - mdpi.com
The Western diet is a modern dietary pattern characterized by high intakes of pre-packaged
foods, refined grains, red meat, processed meat, high-sugar drinks, candy, sweets, fried …

[HTML][HTML] The updated landscape of tumor microenvironment and drug repurposing

MZ Jin, WL Jin - Signal transduction and targeted therapy, 2020 - nature.com
Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …

[HTML][HTML] Obesity shapes metabolism in the tumor microenvironment to suppress anti-tumor immunity

AE Ringel, JM Drijvers, GJ Baker, A Catozzi… - Cell, 2020 - cell.com
Obesity is a major cancer risk factor, but how differences in systemic metabolism change the
tumor microenvironment (TME) and impact anti-tumor immunity is not understood. Here, we …

[HTML][HTML] Excess body weight: Novel insights into its roles in obesity comorbidities

X Zhang, S Ha, HCH Lau, J Yu - Seminars in cancer biology, 2023 - Elsevier
Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

[HTML][HTML] Early-onset colorectal cancer: A review of current knowledge

MR Saraiva, I Rosa, I Claro - World journal of gastroenterology, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Although
most prevalent among older people, its incidence above 50 years old has been decreasing …

Early-onset colorectal cancer: initial clues and current views

LJ Hofseth, JR Hebert, A Chanda, H Chen… - Nature reviews …, 2020 - nature.com
Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …

Global patterns and trends in colorectal cancer incidence in young adults

RL Siegel, LA Torre, I Soerjomataram, RB Hayes… - Gut, 2019 - gut.bmj.com
Objective Early-onset colorectal cancer (CRC) is increasing in the USA despite rapid
declines in older ages. Similar patterns are reported in Australia and Canada, but a …

[HTML][HTML] Global burden of breast cancer and attributable risk factors in 195 countries and territories, from 1990 to 2017: results from the Global Burden of Disease …

NA Li, Y Deng, L Zhou, T Tian, S Yang, Y Wu… - Journal of hematology & …, 2019 - Springer
Background Statistical data on the incidence, mortality, and burden of breast cancer and the
relevant risk factors are valuable for policy-making. We aimed to estimate breast cancer …

Epidemiology and mechanisms of the increasing incidence of colon and rectal cancers in young adults

EM Stoffel, CC Murphy - Gastroenterology, 2020 - Elsevier
In contrast to the decreasing incidence of colorectal cancer (CRC) in older populations, the
incidence has nearly doubled in younger adults since the early 1990s. Approximately 1 in …