Gastrointestinal (GI) vagal afferents convey sensory signals from the GI tract to the brain.
Numerous subtypes of GI vagal afferent have been identified but their individual roles in gut …

The Microbiota-gut-brain axis describes the bidirectional communication between central
nervous system and microorganisms in the gastrointestinal tract. Increasing evidence has …

Recent clinical and experimental evidence has evoked the concept of the gut–brain axis to
explain mutual interactions between the central nervous system and gut microbiota that are …

Multicellular organisms have co-evolved with complex consortia of viruses, bacteria, fungi
and parasites, collectively referred to as the microbiota. In mammals, changes in the …

Food intake is tightly regulated by complex and coordinated gut-brain interactions. Nutrients
rapidly modulate activity in key populations of hypothalamic neurons that regulate food …

Interactions between the enteric nervous system (ENS) and intestinal epithelium are thought
to play a vital role in intestinal homeostasis. How the ENS monitors the frontier with …

Vagus nerve stimulation (VNS) suppresses inflammation and autoimmune diseases in
preclinical and clinical studies. The underlying molecular, neurological, and anatomical …

Background Severe COVID-19 is characterized by pro-inflammatory cytokine release
syndrome (cytokine storm) which causes high morbidity and mortality. Recent observational …

BACKGROUND: The gut hormone GLP-2 (glucagon-like peptide-2) plays important roles in
lipid handling in the intestine. During postabsorptive stage, it releases preformed …

Locomotor activity is an innate behavior that can be triggered by gut-motivated conditions,
such as appetite and metabolic condition. Various nutrient-sensing receptors distributed in …