Ultra-high-performance liquid chromatography high-resolution mass spectrometry variants for metabolomics research
Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …
[HTML][HTML] Natural products in drug discovery: advances and opportunities
AG Atanasov, SB Zotchev, VM Dirsch… - Nature reviews Drug …, 2021 - nature.com
Natural products and their structural analogues have historically made a major contribution
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
Ion mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics
The metabolome includes not just known but also unknown metabolites; however,
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …
Metabolomics in the context of plant natural products research: From sample preparation to metabolite analysis
Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …
compounds for drug development. Natural extracts are usually composed of hundreds to …
Advances in decomposing complex metabolite mixtures using substructure-and network-based computational metabolomics approaches
Covering: up to the end of 2020 Recently introduced computational metabolome mining
tools have started to positively impact the chemical and biological interpretation of …
tools have started to positively impact the chemical and biological interpretation of …
Unraveling plant natural chemical diversity for drug discovery purposes
E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …
benefit from the immense natural chemical diversity is a concern in many laboratories …
Natural products targeting strategies involving molecular networking: different manners, one goal
Covering: up to 2019 Landmark advances in bioinformatics tools have recently enhanced
the field of natural products research, putting today's natural product chemists in the …
the field of natural products research, putting today's natural product chemists in the …
Metabolomics: a systems biology approach for enhancing heat stress tolerance in plants
A Raza - Plant cell reports, 2022 - Springer
Key message Comprehensive metabolomic investigations provide a large set of stress-
related metabolites and metabolic pathways, advancing crops under heat stress conditions …
related metabolites and metabolic pathways, advancing crops under heat stress conditions …
Sprouts and microgreens: Trends, opportunities, and horizons for novel research
A Galieni, B Falcinelli, F Stagnari, A Datti, P Benincasa - Agronomy, 2020 - mdpi.com
Sprouts and microgreens have attracted tremendous interest across multiple disciplines in
recent years. Here, we critically review the most recent advances to underscore research …
recent years. Here, we critically review the most recent advances to underscore research …
A convolutional neural network-based approach for the rapid annotation of molecularly diverse natural products
This report describes the first application of the novel NMR-based machine learning tool
“Small Molecule Accurate Recognition Technology”(SMART 2.0) for mixture analysis and …
“Small Molecule Accurate Recognition Technology”(SMART 2.0) for mixture analysis and …