Neurosteroid actions in memory and neurologic/neuropsychiatric disorders

MH Ratner, V Kumaresan, DH Farb - Frontiers in endocrinology, 2019 - frontiersin.org
Memory dysfunction is a symptomatic feature of many neurologic and neuropsychiatric
disorders; however, the basic underlying mechanisms of memory and altered states of …

Facial emotion recognition and amygdala activation are associated with menstrual cycle phase

B Derntl, C Windischberger, S Robinson… - …, 2008 - Elsevier
Converging evidence has accumulated that menstrual cycle and thus hormonal levels can
affect emotional behavior, in particular facial emotion recognition. Here we explored the …

Novel perspectives for progesterone in hormone replacement therapy, with special reference to the nervous system

M Schumacher, R Guennoun, A Ghoumari… - Endocrine …, 2007 - academic.oup.com
The utility and safety of postmenopausal hormone replacement therapy has recently been
put into question by large clinical trials. Their outcome has been extensively commented …

[HTML][HTML] The human corpus luteum: life cycle and function in natural cycles

L Devoto, A Fuentes, P Kohen, P Céspedes… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To summarize recent advances in the understanding of the endocrine
signaling pathways between the hypothalamus, pituitary, and human corpus luteum (CL); to …

Neurosteroids (allopregnanolone) and alcohol use disorder: from mechanisms to potential pharmacotherapy

E Gatta, D Camussi, J Auta, A Guidotti… - Pharmacology & …, 2022 - Elsevier
Abstract Alcohol Use Disorder (AUD) is a multifaceted relapsing disorder that is commonly
comorbid with psychiatric disorders, including anxiety. Alcohol exposure produces a …

Neurosteroids in the context of stress: implications for depressive disorders

SS Girdler, R Klatzkin - Pharmacology & therapeutics, 2007 - Elsevier
Animal models indicate that the neuroactive steroids 3α, 5α-THP (allopregnanolone) and 3α,
5α-THDOC (allotetrahydroDOC) are stress responsive, serving as homeostatic mechanisms …

The menstrual cycle influences emotion but has limited effect on cognitive function

I Sundström-Poromaa - Vitamins and hormones, 2018 - Elsevier
From a psychological perspective, the menstrual cycle has been a research topic for more
than 50 years. The most recent menstrual cycle research has been driven by an increased …

[HTML][HTML] Strategies to cope with stress and anxiety during the menopausal transition

P Stute, S Lozza-Fiacco - Maturitas, 2022 - Elsevier
The menopausal transition is often accompanied by psycho-vegetative symptoms, including
stress and anxiety symptoms. Identifying stress and anxiety and intervening early can have …

How progesterone impairs memory for biologically salient stimuli in healthy young women

G Van Wingen, F Van Broekhoven… - Journal of …, 2007 - Soc Neuroscience
Progesterone, or rather its neuroactive metabolite allopregnanolone, modulates amygdala
activity and thereby influences anxiety. Cognition and, in particular, memory are also altered …

The role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disorders

G MacKenzie, J Maguire - Psychopharmacology, 2014 - Springer
Rationale Neuroactive derivatives of steroid hormones, neurosteroids, can act on GABA A
receptors (GABA A Rs) to potentiate the effects of GABA on these receptors. Neurosteroids …