[HTML][HTML] Pregnancy in women with monogenic diabetes due to pathogenic variants of the glucokinase gene: lessons and challenges
J Timsit, C Ciangura, D Dubois-Laforgue… - Frontiers in …, 2022 - frontiersin.org
Heterozygous loss-of-function variants of the glucokinase (GCK) gene are responsible for a
subtype of maturity-onset diabetes of the young (MODY). GCK-MODY is characterized by a …
subtype of maturity-onset diabetes of the young (MODY). GCK-MODY is characterized by a …
Maternal and infant outcomes in GCK-MODY complicated by pregnancy
Q Ren, Z Wang, W Yang, X Han… - The Journal of Clinical …, 2023 - academic.oup.com
Context Challenges exist in the management of Glucokinase–maturity-onset diabetes of the
young (GCK-MODY), especially during pregnancy. Objective This work aimed to evaluate …
young (GCK-MODY), especially during pregnancy. Objective This work aimed to evaluate …
[HTML][HTML] Bringing precision medicine to the management of pregnancy in women with glucokinase-MODY: a study of diagnostic accuracy and feasibility of non …
AE Hughes, JAL Houghton, B Bunce, AJ Chakera… - Diabetologia, 2023 - Springer
Aims/hypothesis In pregnancies where the mother has glucokinase-MODY (GCK-MODY),
fetal growth is determined by fetal genotype. When the fetus inherits a maternal pathogenic …
fetal growth is determined by fetal genotype. When the fetus inherits a maternal pathogenic …
Genetic counseling in diabetes mellitus: A practice resource of the National Society of Genetic Counselors
KA Maloney, E Mizerik, RH King… - Journal of Genetic …, 2023 - Wiley Online Library
Diabetes mellitus is a group of diseases characterized by hyperglycemia and its
consequences, affecting over 34 million individuals in the United States and 422 million …
consequences, affecting over 34 million individuals in the United States and 422 million …
Enhancing fetal outcomes in GCK-MODY pregnancies: a precision medicine approach via non-invasive prenatal GCK mutation detection
VM Schwitzgebel, JL Blouin, B Dehos… - Frontiers in …, 2024 - frontiersin.org
Background Mutations in the GCK gene cause Maturity Onset Diabetes of the Young (GCK-
MODY) by impairing glucose-sensing in pancreatic beta cells. During pregnancy, managing …
MODY) by impairing glucose-sensing in pancreatic beta cells. During pregnancy, managing …
Diagnosis and management of monogenic diabetes in pregnancy
S Edensor, O Jones, AJ Chakera - Current Diabetes Reviews, 2023 - ingentaconnect.com
Monogenic diabetes occurs in up to 3% of people with diabetes. Mutations in over 40
different genes are responsible. The most common genes affected are HNF1A, HNF4A …
different genes are responsible. The most common genes affected are HNF1A, HNF4A …
[PDF][PDF] Maturity-onset diabetes of the young og graviditet
A Kauffmann, IL Jørgensen, AC Thuesen… - Ugeskr …, 2023 - content.ugeskriftet.dk
Maturity-onset diabetes of the young (MODY) er en gruppe af monogene diabetesformer.
Aktuelt er der beskrevet 14 forskellige undertyper, der alle skyldes funktionelle varianter i …
Aktuelt er der beskrevet 14 forskellige undertyper, der alle skyldes funktionelle varianter i …
Window of opportunity: screening for GCK monogenic diabetes in the antenatal diabetes clinic
A Surendran, A Brackenridge, SL White - Practical Diabetes, 2022 - Wiley Online Library
Monogenic diabetes (MODY) is a rare, inherited form of diabetes, of which glucokinase
(GCK) mutation is one of the most common forms. Correct diagnosis is important, particularly …
(GCK) mutation is one of the most common forms. Correct diagnosis is important, particularly …
[HTML][HTML] Maturity-Onset Diabetes of the Young (MODY)
SS Park, SH Kwak - The Journal of Korean Diabetes - synapse.koreamed.org
요약 앞으로 정밀의료는 개인별 특성에 맞게 당뇨병의 진단, 분류, 치료를 보다 구체화시키는 데
일조할 것이다. 단일유전자당뇨병에 있어서는 이러한 변화가 이미 두드러지게 나타나고 있다 …
일조할 것이다. 단일유전자당뇨병에 있어서는 이러한 변화가 이미 두드러지게 나타나고 있다 …