Background: Opioids are frequently prescribed for chronic low back pain (CLBP), but there
are little prospective data on which patient subgroups may benefit. Psychiatric comorbidity …

This article reviews the pharmacology and physiology of opiate receptors and the current
and potential uses of opioid agonists and antagonists in clinical gastroenterology. μ …

Chronic, nonmalignant pain is a substantial public health problem in the United States.
Research over the past 2 decades has defined chronic pain by using a “biopsychosocial …

Objective To evaluate the outcomes associated with the use of controlled-release (CR)
oxycodone for up to 3 years in the treatment of noncancer pain. Methods Adult patients who …

Pain Physician: May 2007 10: 399-424 400 www. painphysicianjournal. com erate the
growing problem of illicit drug use and prescription controlled substance abuse. Yet, the …

Use of opioids for chronic non-cancer pain is increasing, but the clinical epidemiology and
standards of care for this practice are poorly defined. Psychiatric disorders are associated …

The Screener and Opioid Assessment for Patients with Pain (SOAPP) is a brief, self-
administered screening instrument used to assess suitability of long-term opioid therapy for …

Placebo treatments and opiate drugs are thought to have common effects on the opioid
system and pain-related brain processes. This has created excitement about the potential for …

AIM: To evaluate intensity, localization and cofactors of pain in Crohn's disease and
ulcerative colitis patients in connection with health-related quality of life (HRQOL) and …

Little is known about patients prescribed high doses of opioids to treat chronic non-cancer
pain, though these patients may be at higher risk for medication-related complications. We …