[HTML][HTML] The broad spectrum of human natural killer cell diversity
Natural killer (NK) cells provide protection against infectious pathogens and cancer. For
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …
[HTML][HTML] GABAergic signaling by cells of the immune system: more the rule than the exception
AK Bhandage, A Barragan - Cellular and Molecular Life Sciences, 2021 - Springer
Gamma-aminobutyric acid (GABA) is best known as an essential neurotransmitter in the
evolved central nervous system (CNS) of vertebrates. However, GABA antedates the …
evolved central nervous system (CNS) of vertebrates. However, GABA antedates the …
CMV and natural killer cells: shaping the response to vaccination
Cytomegaloviruses (CMVs) are highly prevalent, persistent human pathogens that not only
evade but also shape our immune responses. Natural killer (NK) cells play an important role …
evade but also shape our immune responses. Natural killer (NK) cells play an important role …
[HTML][HTML] NK cells and other cytotoxic innate lymphocytes in colorectal cancer progression and metastasis
Colorectal cancer (CRC) is one of the most common malignancies and leading causes of
cancer-related deaths worldwide. Despite its complex pathogenesis and progression, CRC …
cancer-related deaths worldwide. Despite its complex pathogenesis and progression, CRC …
[HTML][HTML] Endothelial cells express NKG2D ligands and desensitize antitumor NK responses
TW Thompson, AB Kim, PJ Li, J Wang, BT Jackson… - Elife, 2017 - elifesciences.org
Natural Killer (NK) cells confer protection from tumors and infections by releasing cytotoxic
granules and pro-inflammatory cytokines upon recognition of diseased cells. The …
granules and pro-inflammatory cytokines upon recognition of diseased cells. The …
Immunity at maternal–fetal interface: KIR/HLA (Allo) recognition
M Alexandrova, D Manchorova… - Immunological …, 2022 - Wiley Online Library
Both KIR and HLA are the most variable gene families in the human genome. The
recognition of the semi‐allogeneic embryo‐derived trophoblasts by maternal decidual NK …
recognition of the semi‐allogeneic embryo‐derived trophoblasts by maternal decidual NK …
[HTML][HTML] Expression of CD226 is associated to but not required for NK cell education
Abstract DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an activating
receptor expressed on subsets of natural killer (NK) and T cells, interacts with its ligands …
receptor expressed on subsets of natural killer (NK) and T cells, interacts with its ligands …
[HTML][HTML] Remodeling of the host cell plasma membrane by HIV-1 Nef and Vpu: a strategy to ensure viral fitness and persistence
The plasma membrane protects the cell from its surroundings and regulates cellular
communication, homing, and metabolism. Not surprisingly, the composition of this …
communication, homing, and metabolism. Not surprisingly, the composition of this …
The yin‐yang of the interaction between myelomonocytic cells and NK cells
M Molgora, D Supino, D Mavilio… - Scandinavian …, 2018 - Wiley Online Library
NK cells are innate lymphoid cells, which play a key role in the immune response to cancer
and pathogens and participate in the shaping of adaptive immunity. NK cells engage in a …
and pathogens and participate in the shaping of adaptive immunity. NK cells engage in a …
[HTML][HTML] PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype
Although PD-1 was shown to be a hallmark of T cells exhaustion, controversial studies have
been reported on the role of PD-1 on NK cells. Here, we found by flow cytometry and single …
been reported on the role of PD-1 on NK cells. Here, we found by flow cytometry and single …