Glutathione (GSH) is the most abundant non-protein thiol present at millimolar
concentrations in mammalian tissues. As an important intracellular antioxidant, it acts as a …

Methylation of arginine residues by protein arginine methyltransferases (PRMTs) is involved
in the regulation of fundamental cellular processes, including transcription, RNA processing …

Macrophages are the most abundant cells within the tumor stroma displaying noticeable
plasticity, which allows them to perform several functions within the tumor microenvironment …

Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …

Periodontal disease is one of the most common oral infectious diseases and closely related
to many systemic diseases which is in urgent need of novel and effective drugs. In particular …

Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

Nitric Oxide (NO) is a soluble endogenous gas with various biological functions like
signaling, and working as an effector molecule or metabolic regulator. In response to …

Simple Summary Internationally, in women, breast cancer (BC) is the most common cancer
type and is the leading cause of cancer-related death. There are two main histological …

Regulatory T cells (Tregs) represent a low number of T‐cell population under normal
conditions, and they play key roles for maintaining immune system in homeostasis. The …

Tumor microenvironment (TME) is a host for a complex network of heterogeneous stromal
cells with overlapping or opposing functions depending on the dominant signals within this …