EMT: Present and future in clinical oncology

PG Santamaria, G Moreno‐Bueno, F Portillo… - Molecular …, 2017 - Wiley Online Library
Epithelial/mesenchymal transition (EMT) has emerged as a key regulator of metastasis by
facilitating tumor cell invasion and dissemination to distant organs. Recent evidences …

Aspects of the epigenetic regulation of EMT related to cancer metastasis

E Nowak, I Bednarek - Cells, 2021 - mdpi.com
Epithelial to mesenchymal transition (EMT) occurs during the pathological process
associated with tumor progression and is considered to influence and promote the …

The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment

H Cessna, S Baritaki, A Zaravinos, B Bonavida - Cancers, 2022 - mdpi.com
Simple Summary Raf kinase inhibitor protein (RKIP) expression in cancer cells is
significantly reduced and promoting cancer cells growth and invasiveness. Overexpresssion …

E-cadherin on epithelial–mesenchymal transition in thyroid cancer

X Zhu, X Wang, Y Gong, J Deng - Cancer Cell International, 2021 - Springer
Thyroid carcinoma is a common malignant tumor of endocrine system and head and neck.
Recurrence, metastasis and high malignant expression after routine treatment are serious …

[HTML][HTML] SDC4 gene silencing favors human papillary thyroid carcinoma cell apoptosis and inhibits epithelial mesenchymal transition via Wnt/β-catenin pathway

LL Chen, GX Gao, FX Shen, X Chen, XH Gong… - Molecules and cells, 2018 - Elsevier
As the most common type of endocrine malignancy, papillary thyroid cancer (PTC) accounts
for 85–90% of all thyroid cancers. In this study, we presented the hypothesis that SDC4 gene …

BACH1 promotes the progression of esophageal squamous cell carcinoma by inducing the epithelial–mesenchymal transition and angiogenesis

Y Zhao, J Gao, X Xie, P Nan, F Liu, Y Sun… - Cancer …, 2021 - Wiley Online Library
Metastasis to regional lymph nodes or distal organs predicts the progression of the disease
and poor prognosis in esophageal squamous cell carcinoma (ESCC). Previous studies …

[HTML][HTML] Emerging insights into the biology of metastasis: A review article

S Irani - Iranian journal of basic medical sciences, 2019 - ncbi.nlm.nih.gov
Metastasis means the dissemination of the cancer cells from one organ to another which is
not directly connected to the primary site. Metastasis has a crucial role in the prognosis of …

Human amniotic membrane inhibits migration and invasion of muscle-invasive bladder cancer urothelial cells by downregulating the FAK/PI3K/Akt/mTOR signalling …

A Janev, TŽ Ramuta, UD Jerman, H Obradović… - Scientific Reports, 2023 - nature.com
Bladder cancer is the 10th most commonly diagnosed cancer with the highest lifetime
treatment costs. The human amniotic membrane (hAM) is the innermost foetal membrane …

N-cadherin overexpression enhances the reparative potency of human-induced pluripotent stem cell-derived cardiac myocytes in infarcted mouse hearts

X Lou, M Zhao, C Fan, VG Fast… - Cardiovascular …, 2020 - academic.oup.com
Aims In regenerative medicine, cellular cardiomyoplasty is one of the promising options for
treating myocardial infarction (MI); however, the efficacy of such treatment has shown to be …

Dexamethasone inhibits spheroid formation of thyroid cancer cells exposed to simulated microgravity

D Melnik, J Sahana, TJ Corydon, S Kopp, MZ Nassef… - Cells, 2020 - mdpi.com
Detachment and the formation of spheroids under microgravity conditions can be observed
with various types of intrinsically adherent human cells. In particular, for cancer cells this …