Clinical implications of (epi) genetic changes in HPV-induced cervical precancerous lesions

RDM Steenbergen, PJF Snijders… - Nature Reviews …, 2014 - nature.com
Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …

Drug repurposing for viral cancers: A paradigm of machine learning, deep learning, and virtual screening‐based approaches

F Ahmed, IS Kang, KH Kim, A Asif… - Journal of Medical …, 2023 - Wiley Online Library
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …

MicroRNAs as markers of progression in cervical cancer: a systematic review

B Pardini, D De Maria, A Francavilla, C Di Gaetano… - BMC cancer, 2018 - Springer
Background Invasive cervical cancer (ICC) is caused by high-risk human papillomavirus
types (HR-HPVs) and is usually preceded by a long phase of intraepithelial neoplasia (CIN) …

Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective

M Kori, K Yalcin Arga - PLoS One, 2018 - journals.plos.org
The malignant neoplasm of the cervix, cervical cancer, has effects on the reproductive tract.
Although infection with oncogenic human papillomavirus is essential for cervical cancer …

The 2012 nucleic acids research database issue and the online molecular biology database collection

MY Galperin, XM Fernández-Suarez - Nucleic acids research, 2012 - academic.oup.com
Abstract The 19th annual Database Issue of Nucleic Acids Research features descriptions of
92 new online databases covering various areas of molecular biology and 100 papers …

Genomic risk factors for cervical cancer

D Ramachandran, T Dörk - Cancers, 2021 - mdpi.com
Simple Summary Cervical cancer is the fourth leading cause of cancer-related deaths in
females worldwide. Despite an active immunisation strategy in many countries, high-risk …

Human cancer databases

A Pavlopoulou, DA Spandidos… - Oncology …, 2015 - spandidos-publications.com
Cancer is one of the four major non‑communicable diseases (NCD), responsible for~ 14.6%
of all human deaths. Currently, there are> 100 different known types of cancer and> 500 …

HPVTIMER: A shiny web application for tumor immune estimation in human papillomavirus‐associated cancers

L Liu, Y Xie, H Yang, A Lin, M Dong, H Wang, C Zhang… - Imeta, 2023 - Wiley Online Library
The tumor immune microenvironment (TIME) is closely associated with tumor formation,
particularly linked to the human papillomavirus (HPV), and regulates tumor initiation …

A comprehensive review of dysregulated miRNAs involved in cervical cancer

G Sharma, P Dua, S Mohan Agarwal - Current genomics, 2014 - ingentaconnect.com
MicroRNAs (miRNAs) have become the center of interest in oncology. In recent years,
various studies have demonstrated that miRNAs regulate gene expression by influencing …

[HTML][HTML] Global variation of human papillomavirus genotypes and selected genes involved in cervical malignancies

RSA Husain, V Ramakrishnan - Annals of global health, 2015 - Elsevier
Background Carcinoma of the cervix is ranked second among the top 5 cancers affecting
women globally. Parallel to other cancers, it is also a complex disease involving numerous …