RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure
Abstract Increased cytochrome P450 2E1 (CYP2E1) expression is the main cause of
oxidative stress, which exacerbates alcoholic liver diseases (ALDs). Estrogen-related …
oxidative stress, which exacerbates alcoholic liver diseases (ALDs). Estrogen-related …
[HTML][HTML] Impaired Rab7 and dynamin2 block fat turnover by autophagy in alcoholic fatty livers
Alcoholic liver disease (ALD) at early stages is characterized by hepatic steatosis, ie,
excessive accumulation of fat (eg, triglyceride or triacylglycerol, esterified cholesterol) …
excessive accumulation of fat (eg, triglyceride or triacylglycerol, esterified cholesterol) …
Proteomic investigations of transcription factors critical in geniposide-mediated suppression of alcoholic steatosis and in overdose-induced hepatotoxicity on liver in …
J Wei, Q Man, C Ding, Y Hu, M Liu, H Li… - Journal of proteome …, 2019 - ACS Publications
Alcoholic steatosis is one of the most prevalent forms of liver disease, and appropriate
insight and application of anti-steatosis drugs must be considered. Geniposide, the major …
insight and application of anti-steatosis drugs must be considered. Geniposide, the major …
Molecular regulation of miRNAs and potential biomarkers in the progression of hepatic steatosis to NASH
Increasing evidence suggests that microRNAs regulate diverse biological functions in the
liver and play a very important function in metabolic-related disorders such as nonalcoholic …
liver and play a very important function in metabolic-related disorders such as nonalcoholic …
Preventive and therapeutic effects of pigment and polysaccharides in Lycium barbarum on alcohol-induced fatty liver disease in mice
D Li, L Sun, Y Yang, Z Wang, X Yang… - CyTA-Journal of Food, 2018 - Taylor & Francis
This study aims to explore the preventive and therapeutic effects of Lycium barbarum
pigment (LP) and polysaccharides (LBPs) on alcohol-induced fatty liver disease (AFLD) in …
pigment (LP) and polysaccharides (LBPs) on alcohol-induced fatty liver disease (AFLD) in …
Reduced methylation of PP2Ac promotes ethanol–induced lipid accumulation through FOXO1 phosphorylation in vitro and in vivo
Y Zhang, T Yuan, Z Su, X Wang, Y Wang, Y Ni, Y Zuo… - Toxicology Letters, 2020 - Elsevier
Although disturbance of the methionine cycle and sequent decrease in hepatic methylation
capacity are known to be important factors in the development of alcoholic liver injury, the …
capacity are known to be important factors in the development of alcoholic liver injury, the …
Investigation of dysregulated lipid metabolism in diabetic mice via targeted metabolomics of bile acids in enterohepatic circulation
Y Ruan, R Liu, L Gong - Rapid Communications in Mass …, 2022 - Wiley Online Library
Rationale The mechanism of lipid metabolism disorder in type 2 diabetes (T2DM) remains
unclear. This study aimed to reveal the mechanism underlying dysregulated lipid …
unclear. This study aimed to reveal the mechanism underlying dysregulated lipid …
[HTML][HTML] Venta de alcohol y tasa de enfermedad hepática alcohólica por departamentos en Colombia
V Andrade, JD Mosos, B Pacheco… - Revista colombiana de …, 2015 - scielo.org.co
Objetivos: determinar la asociación estadística entre el diagnóstico de enfermedad hepática
alcohólica según Registros Individuales de Prestaciones de Servicios de Salud (RIPS) y …
alcohólica según Registros Individuales de Prestaciones de Servicios de Salud (RIPS) y …
Diethylcarbamazine: Possible therapeutic alternative in the treatment of alcoholic liver disease in C57 BL/6 mice
GB Rodrigues, SWS Rocha, LAM Santos… - Clinical and …, 2015 - Wiley Online Library
Alcoholic liver disease is a major cause of chronic liver disease worldwide.
Diethylcarbamazine (DEC) is a drug that has anti‐inflammatory properties due to its effects …
Diethylcarbamazine (DEC) is a drug that has anti‐inflammatory properties due to its effects …
[HTML][HTML] 白介素-22 在肝损伤中JAK-STAT3 通路作用的研究进展
岑瑜, 郭晓云, 姜海行 - 世界华人消化杂志, 2015 - wjgnet.com
Abstract 白介素-22 (interleukin-22, IL-22) 是IL-10 家族成员之一, 主要是由Th22
细胞分泌的细胞因子, 与特异性表达IL-22 受体的组织细胞相结合, 进而激活信号传导与转录激活 …
细胞分泌的细胞因子, 与特异性表达IL-22 受体的组织细胞相结合, 进而激活信号传导与转录激活 …