Piperacillin/tazobactam versus carbapenems in patients with severe bacterial infections: A systematic review with meta‐analysis

MW Munch, A Granholm, AB Jonsson… - Acta …, 2023 - Wiley Online Library
Background Piperacillin/tazobactam or meropenem are often used to treat patients with
severe bacterial infections. We aimed to compare the desirable and undesirable effects of …

[HTML][HTML] Carbapenem-alternative strategies for complicated urinary tract infections: a systematic review of randomized controlled trials

T ten Doesschate, TW van der Vaart, JAA Damen… - Journal of Infection, 2020 - Elsevier
Highlights•Frequent use of carbapenem increases selection of carbapenem resistant
Enterobacterales•To alleviate this, we reviewed alternative strategies against complicated …

Retrospective analysis of clinical profile prognostic factors and outcomes of 19 patients of emphysematous pyelonephritis

A Khaira, A Gupta, DS Rana, A Gupta, A Bhalla… - … urology and nephrology, 2009 - Springer
Aim We aimed to study the clinical profile, prognostic factors, and the 6-month outcome of
patients with emphysematous pyelonephritis (EPN) Methods All patients admitted with a …

The new treatment paradigm and the role of carbapenems

RG Masterton - International Journal of Antimicrobial Agents, 2009 - Elsevier
The global increase in antibiotic resistance is promoted by the widespread use of broad-
spectrum antibiotics, creating a continuous selective pressure on bacteria. This resistance is …

Treating pneumonia in critical care in the United Kingdom following failure of initial antibiotic: a cost-utility analysis comparing meropenem with piperacillin/tazobactam

SJ Edwards, S Wordsworth, MJ Clarke - The European Journal of Health …, 2012 - Springer
Background Treating patients admitted to critical care with severe pneumonia requires
timely intervention with an effective antibiotic. This reduces the risk of dying of pneumonia …

Prevalence and characteristics of ertapenem-nonsusceptible Escherichia coli in a Taiwanese university hospital, 1999 to 2007

JJ Yan, JJ Wu, CC Lee, WC Ko, FC Yang - European journal of clinical …, 2010 - Springer
The present study was conducted to investigate the prevalence and characteristics of
ertapenem-nonsusceptible (ETP-NS) Escherichia coli in a Taiwanese university. A total of …

Antimicrobial stewardship of β-lactams in intensive care units

MO Cotta, JA Roberts, A Tabah, J Lipman… - Expert review of anti …, 2014 - Taylor & Francis
Stewardship of all antimicrobials, including β-lactam antibiotics, has gained in prominence
over the last decade. Appropriate use of these agents has become vitally important; …

Piperacillin/tazobactam vs carbapenems for patients with bacterial infection: Protocol for a systematic review

MW Petersen, A Perner, F Sjövall… - Acta …, 2019 - Wiley Online Library
Introduction Early empirical broad‐spectrum antimicrobial therapy is recommended for
patients with severe infections, including sepsis. β‐lactam/β‐lactamase inhibitor …

Carbapenems versus other beta-lactams in the treatment of hospitalised patients with infection: a mixed treatment comparison

SJ Edwards, MJ Clarke, S Wordsworth… - … medical research and …, 2009 - Taylor & Francis
Objective: To compare the effectiveness of meropenem with cefepime and piperacillin/
tazobactam in the absence of direct comparisons in randomised controlled trials. Data …

An update on the synthesis and antibacterial effects of carbapenems

AM Galal, W Gul, AM Noreddin… - Recent patents on anti …, 2010 - ingentaconnect.com
The double-edged sword of antibiotic use in the fight against disease has saved countless
lives at the cost of an escalation in pathogenic bacteria with increased resistance to multiple …