The role of SLC26A4 in bony labyrinth development and otoconial mineralization in mouse models
T Ito, H Watanabe, K Honda, T Fujikawa… - Frontiers in Molecular …, 2024 - frontiersin.org
Inner ear malformations are predominantly attributed to developmental arrest during the
embryonic stage of membranous labyrinth development. Due to the inherent difficulty in …
embryonic stage of membranous labyrinth development. Due to the inherent difficulty in …
[HTML][HTML] Quantitative analysis and correlative evaluation of video-oculography, micro-computed tomography, and histopathology in Pendrin-null mice
H Watanabe, T Ito, N Aoki, J Bai, K Honda… - Neurobiology of …, 2023 - Elsevier
Patients with SLC26A4 mutations exhibit highly variable hearing loss and vestibular
dysfunction. Although Slc26a4 mutant mice similarly exhibit vestibular deficits, including …
dysfunction. Although Slc26a4 mutant mice similarly exhibit vestibular deficits, including …
Incomplete Partition Type II Cochlear Malformations: Delineating the Three-Dimensional Structure from Digitized Human Histopathological Specimens
C Swords, A Geerardyn, MY Zhu, JT O'Malley… - Otology & …, 2023 - journals.lww.com
Background IP-II is a commonly implanted cochlear malformation. Detailed knowledge of
intracochlear three-dimensional (3D) morphology may assist with cochlear implant (CI) …
intracochlear three-dimensional (3D) morphology may assist with cochlear implant (CI) …
Three‐dimensionally visualized ossification and mineralization process of the otic capsule in a postnatal developmental mouse
J Bai, T Ito, T Fujikawa, K Honda… - Laryngoscope …, 2023 - Wiley Online Library
Objective We aimed to elucidate the ossification process of the otic capsule in postnatal
C57BL/6 mice and depict the three‐dimensional (3D) process of otoconial mineralization in …
C57BL/6 mice and depict the three‐dimensional (3D) process of otoconial mineralization in …
モデルマウスを用いたPendred 症候群の聴平衡覚障害の病態解明
伊藤卓 - Otology Japan, 2022 - jstage.jst.go.jp
抄録 Pendred 症候群の原因遺伝子である SLC26A4 により合成されるたんぱく質, pendrin
はマウス内耳において蝸牛, 前庭, 内リンパ嚢で発現している. これまでの Slc26a4 KO …
はマウス内耳において蝸牛, 前庭, 内リンパ嚢で発現している. これまでの Slc26a4 KO …