Oxidative stress is involved in the aetiology of defective embryo development. Reactive
oxygen species (ROS) may originate from embryo metabolism and/or embryo surroundings …

Assisted reproductive technology (ART) is a common treatment of choice for many couples
facing infertility issues, be it due to male or female factor, or idiopathic. Employment of ART …

Infertility is a common problem experienced by many couples. Numerous treatments are
available for female infertility. However, in some cases, the treatment is empirical in nature …

BACKGROUND: IVF is limited by low success rates and a confounding high multiple birth
rate contributing to prematurity, increased neonatal mortality and child handicap. These …

Along with the transition from maternal to embryonic genome control the mammalian
preimplantation embryo undergoes significant changes in its physiology during …

A major obstacel to the study of mammalian development, and to the practical application of
knowledge gained from it in the clinic during therapeutic in vitro fertilisation and embryo …

Preimplantation embryonic development is associated with a change in preference in
energy metabolism pathways. Although oxidative phosphorylation is obligatory in most …

The negative effect of oxidative stress on the human reproductive process is no longer a
matter for debate. Oxidative stress affects female and male gametes and the developmental …

Mitochondria play a central and multifaceted role in the mammalian egg and early embryo,
contributing to many different aspects of early development. While the contribution of …

The major endocannabinoid (eCB) 2-arachidonoylglycerol (2-AG) is a member of the
endocannabinoid system (ECS) that participates in cell proliferation and apoptosis …