Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted …

M Liao, R Qin, W Huang, HP Zhu, F Peng… - Journal of Hematology & …, 2022 - Springer
Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Enterotoxigenic Escherichia coli: intestinal pathogenesis mechanisms and colonization resistance by gut microbiota

Y Zhang, P Tan, Y Zhao, X Ma - Gut Microbes, 2022 - Taylor & Francis
Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and
travelers in developing countries. ETEC is characterized by the ability to produce major …

Characterization of triple-negative breast cancer MDA-MB-231 cell spheroid model

Z Huang, P Yu, J Tang - OncoTargets and therapy, 2020 - Taylor & Francis
Background: The tumor three-dimensional (3D) spheroid model in vitro is effective on
detecting malignant cells and tumorigenesis, and assessing drug resistance. Compared with …

Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion

L Si, J Fu, W Liu, T Hayashi, Y Nie, K Mizuno… - Molecular and cellular …, 2020 - Springer
Human triple negative breast cancer cells, MDA-MB-231, show typical epithelial to
mesenchymal transition associated with cancer progression. Mitochondria play a major role …

Colorectal cancer treatment using bacteria: focus on molecular mechanisms

S Ebrahimzadeh, H Ahangari, A Soleimanian… - BMC microbiology, 2021 - Springer
Background Colorectal cancer which is related to genetic and environmental risk factors, is
among the most prevalent life-threatening cancers. Although several pathogenic bacteria …

TGF-β1 promotes autophagy and inhibits apoptosis in breast cancer by targeting TP63

Y Wang, H Lu, Z Wang, Y Li, X Chen - Frontiers in Oncology, 2022 - frontiersin.org
Background Breast cancer (BC) is a prevalent female cancer, which has high morbidity and
mortality. However, the pathogenesis of BC has not been fully elucidated. Studies have …

Bacteria-mediated modulatory strategies for colorectal cancer treatment

AL Mueller, A Brockmueller, N Fahimi, T Ghotbi… - Biomedicines, 2022 - mdpi.com
Colorectal cancer (CRC) is one of the most common tumors worldwide, with a higher rate of
distant metastases than other malignancies and with regular occurrence of drug resistance …

Pathogenic Escherichia coli

Z Peng, X Wang, J Huang, B Li - Molecular Medical Microbiology, 2024 - Elsevier
In a very long time after its first discovery by a Bavarian pediatrician in the late 19th century,
Escherichia coli was recognized as a harmless bacterial species and as a normal flora in the …

Potential role of herbal-and bacterial-derived peptides against colorectal cancer

S Abdoullahi, A Jahangiri, R Halabian - Revista Brasileira de …, 2022 - Springer
Despite recent advances in the prevention, diagnosis, and treatment of colorectal cancer as
the third cause of cancer death, the development of refractory tumor cells results in low …

New Insight into triple-negative breast cancer therapy: The potential roles of endoplasmic reticulum stress and autophagy mechanisms

M Ashrafizadeh, R Mohammadinejad… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
Background: Breast cancer is accounted as the fifth leading cause of mortality among the
other cancers. Notwithstanding, Triple Negative Breast Cancer (TNBC) is responsible for 15 …