Statins and oral biofilm: Simvastatin as a promising drug to control periodontal dysbiosis
RD Parolina de Carvalho, J de Andrade Moreno… - Oral …, 2024 - Wiley Online Library
Objectives This study evaluated antimicrobial activity of atorvastatin, pravastatin,
rosuvastatin, and simvastatin against oral bacteria, and the interaction of simvastatin with …
rosuvastatin, and simvastatin against oral bacteria, and the interaction of simvastatin with …
Effect of Diclofenac and Simvastatin on Bone Defect Healing—An In Vivo Animal Study
T Karanikola, A Cheva, K Sarafidou… - Biomimetics, 2022 - mdpi.com
Non-steroidal, anti-inflammatory drugs and statins are two widely prescribed drug classes
that affect bone formation. The aim of this study was to elucidate the effect of diclofenac and …
that affect bone formation. The aim of this study was to elucidate the effect of diclofenac and …
The evaluation of cytotoxicity and cytokine IL-6 production of root canal sealers with and without the incorporation of simvastatin: an invitro study
Background Freshly mixed root canal sealers when proximate the periapical tissues, trigger
varying degrees of cytotoxicity/inflammatory reactions. Simvastatin, a class of the drug statin …
varying degrees of cytotoxicity/inflammatory reactions. Simvastatin, a class of the drug statin …
New insights on mode of action of vasorelaxant activity of simvastatin
Simvastatin is a semisynthetic inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-
CoA) reductase and is used extensively to treat atherosclerotic cardiovascular disease …
CoA) reductase and is used extensively to treat atherosclerotic cardiovascular disease …
Statins—Their Role in Bone Tissue Metabolism and Local Applications with Different Carriers
MM Granat, J Eifler-Zydel, J Kolmas - International Journal of Molecular …, 2024 - mdpi.com
Statins, widely prescribed for lipid disorders, primarily target 3-hydroxy-3-methylglutaryl-
coenzyme A (HMG-CoA) reductase competitively and reversibly, resulting in reduced low …
coenzyme A (HMG-CoA) reductase competitively and reversibly, resulting in reduced low …
Role of oral health in heart and vascular health: A population-based study
AS Ghanem, O Németh, M Móré, AC Nagy - Plos one, 2024 - journals.plos.org
Background and aim Conditions such as hypertension, cardiovascular diseases, and
hypercholesterolemia, are a major public health challenge. This study investigates the …
hypercholesterolemia, are a major public health challenge. This study investigates the …
Calcium-channel-blocker-influenced gingival enlargement: A conundrum demystified
P Tonsekar, V Tonsekar - Oral, 2021 - mdpi.com
The aim of the article is to discuss the development of calcium channel blocker (CCB)
influenced gingival enlargement. Data and Sources: MEDLINE/PubMed, Scopus …
influenced gingival enlargement. Data and Sources: MEDLINE/PubMed, Scopus …
Hispanic adults with type 2 diabetes mellitus using lipid-lowering agents have better periodontal health than non-users
OM Andriankaja, KJ Joshipura… - … in Chronic Disease, 2023 - journals.sagepub.com
Background: Recent studies suggest that lipid-lowering agents (LLA) may reduce chronic
periodontitis, but it is unknown whether this benefit extends to people with type 2 diabetes …
periodontitis, but it is unknown whether this benefit extends to people with type 2 diabetes …
Enhancing Oral Bioavailability of Simvastatin Using Uncoated and Polymer-Coated Solid Lipid Nanoparticles
AE Abd-Elghany, O El-Garhy, AA Fatease, AH Alamri… - Pharmaceutics, 2024 - mdpi.com
Simvastatin (SVA) is a well-prescribed drug for treating cardiovascular and
hypercholesterolemia. Due to the extensive hepatic first-pass metabolism and poor …
hypercholesterolemia. Due to the extensive hepatic first-pass metabolism and poor …
[HTML][HTML] Evaluation of the Anti-microbial Efficacy of a Novel Endodontic Irrigant Against Enterococcus faecalis: An In Vitro Study
G Selvakumar, A Raveendran, B Swathika, S Ganesan… - Cureus, 2023 - ncbi.nlm.nih.gov
Introduction: Enterococcus faecalis is a constant microbiome that plays an inevitable role in
the etiology of peri radicular lesions after endodontic treatment, chronic and, apical …
the etiology of peri radicular lesions after endodontic treatment, chronic and, apical …