Statins are widely used and have been proven to be effective in the prevention of
atherosclerotic vascular disease events, primarily by reducing plasma low-density …

Introduction: Statins are the cornerstone of lipid-lowering therapy to reduce the risk of
coronary heart disease. Rosuvastatin and pitavastatin are the two recently developed statins …

Memory impairment is a result of multiple factors including amyloid-beta (Aβ) accumulation.
Several receptors are mediated for Aβ transport and signaling. Moreover, blood lipids are …

Background: Atherosclerosis is the leading cause of cardiovascular disease worldwide,
including in China. Primary prevention, through lipid-lowering, could avert development of …

Aim Besides a cholesterol-lowering effect, rosuvastatin (RUV) possesses antioxidant and
anti-inflammatory properties. The present study investigates the possible protective effects of …

Posttraumatic nerve recovery remains a challenge in regenerative medicine. As such, there
is a need for agents that limit nerve damage and enhance nerve regeneration. Here we …

Statins and dietary modifications are the cornerstone of hypercholesterolemia management.
Although it is well known that possible adverse effect of statins can occur due to drug-drug …

Introduction Glioblastoma is a primary intracranial tumour with extremely high disability and
fatality rates among adults. Existing diagnosis and treatment methods have not significantly …

The hepatic Na+-taurocholate cotransporting polypeptide NTCP/SLC10A1 is important for
the uptake of bile salts and selected drugs. Its inhibition results in increased systemic bile …

Background The prevention of cardiac surgery-associated acute kidney injury (CSA-AKI) by
statins remains controversial. Therefore, the present meta-analysis including randomized …