Epigenetic regulations of cellular senescence in osteoporosis

S Huo, X Tang, W Chen, D Gan, H Guo, Q Yao… - Ageing Research …, 2024 - Elsevier
Osteoporosis (OP) is a prevalent age-related disease that is characterized by a decrease in
bone mineral density (BMD) and systemic bone microarchitectural disorders. With age …

[HTML][HTML] Exosomes as a potential therapeutic approach in osteoimmunology

IV Zhivodernikov, YV Markina, TV Kirichenko… - Frontiers in …, 2023 - frontiersin.org
Exosomes are natural extracellular vesicles that play a key role in inter-and intracellular
communication. Currently they are considered as a promising therapeutic strategy for the …

The role of magnesium in the pathogenesis of osteoporosis

L Liu, P Luo, P Wen, P Xu - Frontiers in Endocrinology, 2024 - frontiersin.org
Magnesium (Mg), a nutritional element which is essential for bone development and
mineralization, has a role in the progression of osteoporosis. Osteoporosis is a multifactorial …

[HTML][HTML] Advances in the study of plant-derived extracellular vesicles in the skeletal muscle system

X Mao, T Li, W Qi, Z Miao, L Zhu, C Zhang, H Jin… - Pharmacological …, 2024 - Elsevier
Plant-derived extracellular vesicles (PDEV) constitute nanoscale entities comprising lipids,
proteins, nucleic acids and various components enveloped by the lipid bilayers of plant …

[HTML][HTML] Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease

S Reppe, S Gundersen, GK Sandve, Y Wang… - International Journal of …, 2024 - mdpi.com
Epidemiological evidence suggests existing comorbidity between postmenopausal
osteoporosis (OP) and cardiovascular disease (CVD), but identification of possible shared …

[HTML][HTML] Targeted delivery of anti-osteoporosis therapy: Bisphosphonate-modified nanosystems and composites

S Shi, H Duan, X Ou - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Osteoporosis (OP) constitutes a significant health concern that profoundly affects individuals'
quality of life. Bisphosphonates, conventional pharmaceuticals widely employed in OP …

[HTML][HTML] Defining the most potent osteoinductive culture conditions for MC3T3-E1 cells reveals no implication of oxidative stress or energy metabolism

A Semicheva, U Ersoy, A Vasilaki, I Myrtziou… - International Journal of …, 2024 - mdpi.com
The MC3T3-E1 preosteoblastic cell line is widely utilised as a reliable in vitro system to
assess bone formation. However, the experimental growth conditions for these cells hugely …

MicroRNAs regulate the vicious cycle of vascular calcification-osteoporosis in postmenopausal women

Q Wang, F Peng, J Yang, X Chen, Z Peng… - Molecular Biology …, 2024 - Springer
Menopause is a normal physiological process accompanied by changes in various
physiological states. The incidence of vascular calcification (VC) increases each year after …

Efficacy of Opportunistic Screening with Chest CT in Identifying Osteoporosis and Osteopenia in Patients with T2DM

C Xue, X Lu, G Sun, N Wang, G He, W Xu… - … Syndrome and Obesity, 2024 - Taylor & Francis
Purpose To explore the validity of the thoracic spine Hounsfield Unit (HU) measured by
chest computed tomography (CT) for opportunistic screening of diabetic osteoporosis. The …

[HTML][HTML] Sociodemographic and Lifestyle Risk Factors Associated with Fragility Hip Fractures: A Systematic Review and Meta-Analysis

D Yeritsyan, K Momenzadeh, A Mohamadi… - Osteology, 2024 - mdpi.com
Hip fractures inflict heightened morbidity and mortality upon older adults. Although previous
studies have explored the impact of individual demographic factors on hip fracture risk, a …