[HTML][HTML] Apixaban use in obese patients: a review of the pharmacokinetic, interventional, and observational study data
MJ Jamieson, W Byon, RW Dettloff, M Crawford… - American Journal of …, 2022 - Springer
Relatively little is known about the influence of extreme body weight on the
pharmacokinetics (PK), pharmacodynamics (PD), efficacy, and safety of drugs used in many …
pharmacokinetics (PK), pharmacodynamics (PD), efficacy, and safety of drugs used in many …
[HTML][HTML] Effectiveness of direct oral anticoagulants in obese adults with atrial fibrillation: a systematic review of systematic reviews and meta-analysis
Background: Atrial Fibrillation (AF) is the most common sustained cardiac arrhythmia.
Obesity is an independent risk factor for AF. Anticoagulants have been strongly …
Obesity is an independent risk factor for AF. Anticoagulants have been strongly …
Evaluation of safety and efficacy outcomes of direct oral anticoagulants versus warfarin in normal and extreme body weights for the treatment of atrial fibrillation or …
AR Novak, C Shakowski, TC Trujillo, GC Wright… - Journal of Thrombosis …, 2022 - Springer
Despite evolving evidence, the use of direct oral anticoagulants (DOACs) in patients with
extremes of body weight remains controversial. This study aimed to measure the impact of …
extremes of body weight remains controversial. This study aimed to measure the impact of …
Safety and efficacy of direct oral anticoagulants across body mass index groups in patients with venous thromboembolism: a retrospective cohort design
RM Cardinal, F D'Amico, A D'Addezio, K Dakers… - Journal of Thrombosis …, 2021 - Springer
Current literature on the safety and efficacy of direct oral anticoagulants (DOACs) in patients
of extreme weights are limited, however, they are still being prescribed in these populations …
of extreme weights are limited, however, they are still being prescribed in these populations …
A review of indications and comorbidities in which warfarin may be the preferred oral anticoagulant
D Wadsworth, E Sullivan, T Jacky… - Journal of clinical …, 2021 - Wiley Online Library
What is known and objective Direct oral anticoagulants (DOACs) are increasingly prescribed
instead of warfarin for chronic anticoagulation for ease of dosing, fewer interactions, and …
instead of warfarin for chronic anticoagulation for ease of dosing, fewer interactions, and …
DOAC compared with warfarin for VTE in patients with obesity: a retrospective cohort study conducted through the VENUS network
KA Martin, N Lancki, C Li, ME Eyster… - Journal of thrombosis …, 2023 - Springer
The effectiveness and safety of direct oral anticoagulants (DOAC) compared with warfarin
remains uncertain in obese patients. We assessed the comparative effectiveness and safety …
remains uncertain in obese patients. We assessed the comparative effectiveness and safety …
Direct oral anticoagulants versus warfarin in morbidly obese patients with nonvalvular atrial fibrillation: a systematic review and meta-analysis
Background: Direct oral anticoagulants (DOACs) have been increasingly preferred over
warfarin; however, The International Society of Thrombosis and Hemostasis recommended …
warfarin; however, The International Society of Thrombosis and Hemostasis recommended …
[HTML][HTML] Direct Oral Anticoagulants for Stroke Prevention in Special Populations: Beyond the Clinical Trials
A Carbone, R Bottino, A D'Andrea, V Russo - Biomedicines, 2023 - mdpi.com
Currently, direct oral anticoagulants (DOACs) are the first-line anticoagulant strategy in
patients with non-valvular atrial fibrillation (NVAF). They are characterized by a more …
patients with non-valvular atrial fibrillation (NVAF). They are characterized by a more …
Oral anticoagulant use in patients with morbid obesity: a systematic review and meta-analysis
Objectives Obesity is associated with increased risks of atrial fibrillation (AF) and venous
thromboembolism (VTE) for which anticoagulation is commonly used. However, data on the …
thromboembolism (VTE) for which anticoagulation is commonly used. However, data on the …
Use of direct‐acting oral anticoagulants in solid organ transplantation: A systematic review
AL Bixby, AB Lichvar, D Salerno… - … : The Journal of Human …, 2021 - Wiley Online Library
The use of direct‐acting oral anticoagulants (DOACs) has increased secondary to the
mounting evidence for comparable efficacy and potentially superior safety to vitamin K …
mounting evidence for comparable efficacy and potentially superior safety to vitamin K …