The c-Jun N-terminal kinases (JNKs), as members of the mitogen-activated protein kinase
(MAPK) family, mediate eukaryotic cell responses to a wide range of abiotic and biotic stress …

Tumor cells exist in close proximity with non-malignant cells. Extensive and multilayered
crosstalk between tumor cells and stromal cells tailors the tumor microenvironment (TME) to …

Abstract 'Breast cancer gene-expression miner'(bc-GenExMiner) is a breast cancer–
associated web portal (http://bcgenex. ico. unicancer. fr). Here, we describe the development …

The mechanisms behind cancer initiation and progression are not clear. Therefore,
development of clinically relevant models to study cancer biology and drug response in …

Metastasis is the spread of cancer cells from the primary tumour to distant sites and organs
throughout the body. It is the primary cause of cancer morbidity and mortality, and is …

Abstract RNA N 6-methyladenosine (m 6 A) modification and its regulators fine tune gene
expression and contribute to tumorigenesis. This study aims to uncover the essential role …

Over the past years, it has become evident that cancer initiation and progression depends
on several components of the tumor microenvironment, including inflammatory and immune …

Breast cancer is the most frequent cancer among women, and metastases in distant organs
are the leading cause of the cancer‐related deaths. While survival of early‐stage breast …

Over the last few years, the Transforming growth factor-β (TGF-β) has been significantly
considered as an effective and ubiquitous mediator of cell growth. The cytokine, TGF-β is …

Metastasis is the leading cause of cancer death, tumor progression proceeding through
emigration from the primary tumor, gaining access to the circulation, leaving the circulation …