Fear memory

I Izquierdo, CRG Furini, JC Myskiw - Physiological reviews, 2016 - journals.physiology.org
Fear memory is the best-studied form of memory. It was thoroughly investigated in the past
60 years mostly using two classical conditioning procedures (contextual fear conditioning …

[HTML][HTML] Animal models of anxiety disorders and stress

AC Campos, MV Fogaça, DC Aguiar… - Brazilian Journal of …, 2013 - SciELO Brasil
Anxiety and stress-related disorders are severe psychiatric conditions that affect
performance in daily tasks and represent a high cost to public health. The initial observation …

Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function

E Dale, AL Pehrson, T Jeyarajah, Y Li, SC Leiser… - CNS …, 2016 - cambridge.org
The hippocampus plays an important role in emotional and cognitive processing, and both
of these domains are affected in patients with major depressive disorder (MDD). Extensive …

Fear conditioning and extinction in obsessive-compulsive disorder: a systematic review

SE Cooper, JE Dunsmoor - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Laboratory experiments using fear conditioning and extinction protocols help lay the
groundwork for designing, testing, and optimizing innovative treatments for anxiety-related …

[HTML][HTML] Circuits regulating pleasure and happiness—Mechanisms of depression

AJM Loonen, SA Ivanova - Frontiers in Human Neuroscience, 2016 - frontiersin.org
According to our model of the regulation of appetitive-searching vs. distress-avoiding
behaviors, the motivation to display these essential conducts is regulated by two parallel …

The role of the amygdala in anxiety disorders

GL Forster, AM Novick, JL Scholl… - The amygdala-a discrete …, 2012 - books.google.com
Anxiety is a term often used to encompass feelings of apprehension, dread, unease or
similarly unpleasant emotions. Trait anxiety defines the affect of an organism over time and …

Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder

B Sur, B Lee - Journal of Natural Medicines, 2022 - Springer
Post-traumatic stress disorder (PTSD) is a serious mental disorder that can develop after
exposure to extreme stress. Korean red ginseng, whose major active component is …

[HTML][HTML] Myricetin inhibited fear and anxiety-like behaviors by HPA axis regulation and activation of the BDNF-ERK signaling pathway in posttraumatic stress disorder …

B Sur, B Lee - Evidence-Based Complementary and Alternative …, 2022 - hindawi.com
Posttraumatic stress disorder (PTSD) is a stress-related psychiatric or mental disorder
characterized by experiencing a traumatic stress. The cause of such PTSD is dysregulation …

[HTML][HTML] Correlation between frontal lobe oxy-hemoglobin and severity of depression assessed using near-infrared spectroscopy

M Kawano, T Kanazawa, H Kikuyama… - Journal of affective …, 2016 - Elsevier
Introduction The search for objective biomarkers of psychiatric disorders has a long history.
Despite this, no universally accepted instruments or methods to detect biomarkers have …

Maternal separation enhances conditioned fear and decreases the mRNA levels of the neurotensin receptor 1 gene with hypermethylation of this gene in the rat …

H Toda, S Boku, S Nakagawa, T Inoue, A Kato… - PloS one, 2014 - journals.plos.org
Stress during postnatal development is associated with an increased risk for depression,
anxiety disorders, and substance abuse later in life, almost as if mental illness is able to be …