Freshwater harmful algal blooms (HABs) are increasing in number and severity worldwide.
These HABs are chiefly composed of one or more species of cyanobacteria, also known as …

Microcystins are ubiquitous toxins produced by photoautotrophic cyanobacteria. Human
exposures to microcystins occur through the consumption of contaminated drinking water …

Cyanobacteria are ubiquitous in aquatic and terrestrial environments worldwide and include
a number of species producing tumor-promoting hepatotoxins. Human exposure to …

Background: Gut microbial alterations have been linked to chronic liver disease and
hepatocellular carcinoma (HCC). The role of the oral microbiome in liver cancer …

Microcystins are potent hepatotoxins that have become a global health concern in recent
years. Their actions in at-risk populations with pre-existing liver disease is unknown. We …

We have previously shown in a murine model of Non-alcoholic Fatty Liver Disease (NAFLD)
that chronic, low-dose exposure to the Harmful Algal Bloom cyanotoxin microcystin-LR (MC …

Microcystin-LR (MCLR) is a hepatotoxic cyanotoxin reported to cause a phenotype similar to
nonalcoholic steatohepatitis (NASH). NASH is a common progressive liver disease that …

Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease
and represents an increasing public health issue given the limited treatment options and its …

Nonalcoholic steatohepatitis (NASH) causes liver extracellular matrix (ECM) remodeling and
is a risk factor for fibrosis and hepatocellular carcinoma (HCC). Microcystin-LR (MCLR) is a …

Microcystin-LR (MCLR) is a liver and kidney toxin produced by cyanobacteria. Recently, it
was demonstrated that MCLR exposure drives the progression of high fat/high cholesterol …