An unavoidable consequence of aerobic respiration is the generation of reactive oxygen
species (ROS). These may negatively impact development. Nevertheless, a certain amount …

Mitochondria play a central and multifaceted role in the mammalian egg and early embryo,
contributing to many different aspects of early development. While the contribution of …

The role of mitochondria as central determinants of development competence of oocytes
and preimplantation stage embryos is considered in the context of the diverse activities …

Developmental arrest of the preimplantation embryo is a multifactorial condition,
characterized by lack of cellular division for at least 24 hours, hindering the in vitro …

The process of development depends on a number of signaling systems that regulates the
progressive sequence of developmental events. Infertility and neurodevelopmental …

In vitro culture of the embryo is a useful method to treat infertility that shows embryo potential
for selecting the best one to transfer and successfully implantation. However, embryo …

The ability to screen embryos for aneuploidy or inherited disorders in a minimally invasive
manner may represent a major advancement for the future of embryo viability assessment …

Recent genomic studies have shed light on the impact of in vitro culture (IVC) on embryonic
homeostasis and the differential gene expression profiles associated with lower …

Oocyte maturation is vital to attain full competence required for fertilization and
embryogenesis. NLRP14 is preferentially expressed in mammalian oocytes and early …

According to the World Health Organization, infertility affects up to 14% of couples under
reproductive age, leading to an exponential rise in the use of assisted reproduction as a …