Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …

Infectious diseases (such as sepsis, influenza, and malaria), caused by various pathogenic
bacteria and viruses, are widespread across the world. Early and rapid detection of disease …

CRISPR-based detection was often based on the target preamplification to realize the high
sensitivity. Here, we prepared a CRISPR-Cas12a system for the colorimetric detection of …

The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
related proteins (CRISPR/Cas) are regarded as the next generation of molecular diagnostic …

DNA hydrogels are hydrophilic polymer networks formed by DNA cross-linked polymer
backbones or self-assembly of DNA building blocks. Following Watson-Crick base pairing …

The advancement of biosensing has led to increased demands for precise target recognition
and highly sensitive detection. Nanomaterials have emerged as indispensable contributors …

Food safety is one of the greatest public health challenges. Developing ultrasensitive
detection methods for analytes at ultra-trace levels is, therefore, essential. In recent years …

Food safety has always been a major global challenge to human health and the effective
detection of harmful substances in food can reduce the risk to human health. However, the …

MicroRNAs (miRNAs) have emerged as powerful biomarkers for various diseases
diagnosis, yet their clinical application is greatly plagued by the lack of reliable and rapid …

Biomarkers play key roles in the diagnosis, risk assessment, treatment and supervision of
cardiovascular diseases (CVD). Optical biosensors and assays are valuable analytical tools …