The cerebral vascular system stringently regulates cerebral blood flow (CBF). The
components of the blood–brain barrier (BBB) protect the brain from pathogenic infections …

The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …

Aquaporins (AQPs) are a family of small transmembrane proteins that selectively transport
water and other small molecules and ions following an osmotic gradient across cell plasma …

It is strongly believed that aluminum is one of the insalubrious agents because of its
neurotoxicity effects and influences on amyloid β (Aβ) production and tau protein …

Epilepsy is a chronic brain disorder characterized by unprovoked seizures. Mechanisms
underlying seizure activity have been intensely investigated. Alterations in astrocytic …

Waste removal is essential for maintaining homeostasis and the normal function of the
central nervous system (CNS). The glymphatic system based on aquaporin-4 (AQP4) water …

Sjögren's disease (SjD) is a chronic autoimmune sialadenitis resulting in salivary gland
hypofunction with dry mouth symptom. Previous studies showed that lysosome-associated …

Aims This article aims to analyze the baseline distribution of TRPA1, TRPV1, TRPV4, and
TRPM8 channels in human systems at the transcriptional level. Main methods Using the …

Cell migration is an essential process that underlies many physiological processes,
including the immune response, organogenesis in the embryo, and angiogenesis, as well as …

In addition to aquaporin (AQP) classes AQP1, AQP4 and AQP9 known to be expressed in
mammalian brain, our recent transcriptomic analyses identified AQP0 and AQP11 in human …