Cancer is the second leading cause of death worldwide. Majority of recent research efforts in
the field aim to address why cancer resistance to therapy develops and how to overcome or …

Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver
disease with many metabolic comorbidities, such as obesity, diabetes, and cardiovascular …

Background Kidney Renal Clear Cell Carcinoma (KIRC) is one of the most prevalent types
of cancer worldwide. KIRC has a poor prognosis and, to date, immunotherapy based on …

Matrix metalloproteinase‐1 (MMP1) has been reported to play key roles in a variety of
cancers by degrading the extracellular matrix. However, its carcinogenic roles have not …

Our study aimed to explore the effect of cellular senescence and to find potential therapeutic
strategies for gastric cancer. Cellular senescence-related genes were acquired from the …

Background Stomach adenocarcinoma (STAD) is one of the most prevalent malignances,
ranking fifth in incidence and third in mortality among all malignances. Interferon regulatory …

Inflammatory bowel disease (IBD) is an autoimmune disease characterized by unresolved
colitis and epithelial injury. Intestinal microbiota and its interaction with immune system are …

Background Growing findings have demonstrated that interferon regulatory transcription
factor (IRF) family members are linked to the progression of various cancers. However, the …

Background Pancreatic cancer (PC) is a fatal malignancy that frequently involves perineural
invasion (PNI). This study aims to investigate the function and underlying mechanisms of …

Corosolic acid (CA; 2α-hydroxyursolic acid) is a natural pentacyclic triterpenoid with
antioxidant, antitumour and antimetastatic activities against various tumour cells during …