Pharmacological targeting of microglial activation: new therapeutic approach

CY Liu, X Wang, C Liu, HL Zhang - Frontiers in Cellular Neuroscience, 2019 - frontiersin.org
Mounting evidence suggests that neuroinflammation is not just a consequence but a vital
contributor to the development and progression of Parkinson's disease (PD). Microglia in …

A story of the potential effect of non-steroidal anti-inflammatory drugs (NSAIDs) in Parkinson's disease: beneficial or detrimental effects

M Alrouji, HM Al-Kuraishy, AI Al-Gareeb, HM Saad… - …, 2023 - Springer
Parkinson's disease (PD) is an advanced neurodegenerative disease (NDD) caused by the
degeneration of dopaminergic neurons (DNs) in the substantia nigra (SN). As PD is an age …

Novel applications of NSAIDs: Insight and future perspectives in cardiovascular, neurodegenerative, diabetes and cancer disease therapy

E Kaduševičius - International Journal of Molecular Sciences, 2021 - mdpi.com
Once it became clear that inflammation takes place in the modulation of different
degenerative disease including neurodegenerative, cardiovascular, diabetes and cancer …

Protective effects of Cinnamomum verum, Cinnamomum cassia and cinnamaldehyde against 6-OHDA-induced apoptosis in PC12 cells

E Ramazani, M YazdFazeli, SA Emami… - Molecular biology …, 2020 - Springer
Cinnamon (Cinnamomum verum and C. cassia) is a medicinal plant, widely-used as a
culinary spice. It possesses various therapeutic effects and can slow down the progression …

Neuroinflammatory responses in Parkinson's disease: relevance of Ibuprofen in therapeutics

A Singh, P Tripathi, S Singh - Inflammopharmacology, 2021 - Springer
Parkinson's disease (PD) pathogenesis inevitably involves neuroinflammatory responses
attained through contribution of both neuron and glial cells. Investigation done in both …

[HTML][HTML] Neuroinflammation in parkinson's disease and its treatment opportunities

E Çınar, BC Tel, G Şahin - Balkan medical journal, 2022 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a complex, chronic, and progressive neurodegenerative
disease that is characterized by irreversible dopaminergic neuronal loss in the substantia …

Protective effects of Lavandula stoechas L. methanol extract against 6-OHDA-induced apoptosis in PC12 cells

Z Tayarani-Najaran, E Hadipour, SMS Mousavi… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Parkinson's disease (PD) is a neurodegenerative disorder
associated with oxidative stress-induced neuronal damage and death. In European and …

Protective effects of 6‐gingerol on 6‐hydroxydopamine‐induced apoptosis in PC12 cells through modulation of SAPK/JNK and survivin activation

FS Rezazadeh‐Shojaee, E Ramazani… - … of Biochemical and …, 2022 - Wiley Online Library
Due to many therapeutic effects, Ginger (Zingiber officinale) is the most widely used spice
around the world, including in Iran. Due to its potent anti‐inflammatory and antioxidant …

[HTML][HTML] Osthole attenuated cytotoxicity induced by 6-OHDA in SH-SY5Y cells through inhibition of JAK/STAT and MAPK pathways

S Barangi, P Hosseinzadeh, G Karimi… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Natural coumarin called osthole is regarded as a medicinal herb with
widespread applications in Traditional Chinese Medicine. It has various pharmacological …

[HTML][HTML] Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase …

E Nikkhah, F Kalalinia, MA Rezaee… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): Mesenchymal stem cells (MSCs) extensively interact with cancer cells and
other stromal cells in the tumor microenvironment. However, the role of MSCs in colorectal …