Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Neurosecretory protein VGF (non-acronymic) belongs to the granin family of neuropeptides.
VGF and VGF-derived peptides have been repeatedly identified in well-powered and well …

Background Chronically dysregulated neuroinflammation has been implicated in
neurodegenerative dementias, with separate studies reporting increased brain levels of …

Mitochondria are highly dynamic organelles that serve as the primary cellular energy-
generating system. Apart from ATP production, they are essential for many biological …

Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of
dementia, behind Alzheimer's disease (AD). It is now established that cerebral inflammation …

Objective Lewy body dementia (LBD) is the second most common neurodegenerative
dementia, and it causes earlier mortality and more morbidity than Alzheimer's disease …

Clinical trials in dementia with Lewy bodies: the evolving c... : Current Opinion in Neurology
Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient …

Loneliness and social isolation are detrimental to mental health and may lead to cognitive
impairment and neurodegeneration. Although several molecular signatures of loneliness …

Dementia with Lewy bodies and Parkinson's disease dementia are common
neurodegenerative diseases that share similar neuropathological profiles and spectra of …

Inflammatory mechanisms are increasingly recognized as important contributors to the
pathogenesis of neurodegenerative diseases, including Lewy body dementia (LBD). Our …