A global accounting of medically significant scorpions: Epidemiology, major toxins, and comparative resources in harmless counterparts

MJ Ward, SA Ellsworth, GS Nystrom - Toxicon, 2018 - Elsevier
Scorpions are an ancient and diverse venomous lineage, with over 2200 currently
recognized species. Only a small fraction of scorpion species are considered harmful to …

Scorpions and scorpion sting envenoming (scorpionism) in the Arab Countries of the Middle East

ZS Amr, MAA Baker, M Al-Saraireh, DA Warrell - Toxicon, 2021 - Elsevier
The twelve Arab countries of the Middle East are inhabited by 117 species of scorpions of
varying medical importance within six families. Scorpion stings are a very common …

[HTML][HTML] Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the Middle East and North Africa

TP Jenkins, S Ahmadi, MA Bittenbinder… - PLoS neglected …, 2021 - journals.plos.org
The Middle East and Northern Africa, collectively known as the MENA region, are inhabited
by a plethora of venomous animals that cause up to 420,000 bites and stings each year. To …

[HTML][HTML] Evaluating the performance of de novo assembly methods for venom-gland transcriptomics

ML Holding, MJ Margres, AJ Mason, CL Parkinson… - Toxins, 2018 - mdpi.com
Venom-gland transcriptomics is a key tool in the study of the evolution, ecology, function,
and pharmacology of animal venoms. In particular, gene-expression variation and coding …

[HTML][HTML] Why to study peptides from venomous and poisonous animals?

AN de Oliveira, AM Soares, SL Da Silva - International Journal of Peptide …, 2023 - Springer
Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …

[HTML][HTML] Scorpionism by Hemiscorpius spp. in Iran: a review

R Dehghani, F Kamiabi, M Mohammadi - Journal of venomous …, 2018 - SciELO Brasil
Scorpions are distributed throughout Iran and the genus Hemiscorpius is particularly
important in this region. Hemiscorpius lepturus is the most significant species within the …

Venom-gland transcriptomics and venom proteomics of the Hentz striped scorpion (Centruroides hentzi; Buthidae) reveal high toxin diversity in a harmless member of …

MJ Ward, SA Ellsworth, DR Rokyta - Toxicon, 2018 - Elsevier
Of the 14 extant scorpion families, Buthidae has the most thoroughly characterized venoms.
Most of this characterization, however, has been limited to species with medically significant …

New insights about scorpion venom hyaluronidase; isoforms, expression and phylogeny

F Salabi, H Jafari - Toxin reviews, 2023 - Taylor & Francis
Venom hyaluronidase is an enzyme belonging to the glycoside hydrolase family that plays a
critical role in systemic envenomation by spreading toxins in tissue and destruction of the …

Nanobodies as novel therapeutic agents in envenomation

E Alirahimi, F Kazemi-Lomedasht… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Background An effective therapy against envenoming should be a priority in view of the high
number scorpion stings and snakebites. Serum therapy is still widely applied to treat the …

[HTML][HTML] Proteomic and transcriptomic techniques to decipher the molecular evolution of venoms

S Mouchbahani-Constance, R Sharif-Naeini - Toxins, 2021 - mdpi.com
Nature's library of venoms is a vast and untapped resource that has the potential of
becoming the source of a wide variety of new drugs and therapeutics. The discovery of these …