[HTML][HTML] Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …

Concise review: multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine

RM Samsonraj, M Raghunath… - Stem cells …, 2017 - academic.oup.com
Mesenchymal stem cells (MSC) hold great potential for regenerative medicine because of
their ability for self-renewal and differentiation into tissue-specific cells such as osteoblasts …

Recent trends in cancer therapy: A review on the current state of gene delivery

EB Yahya, AM Alqadhi - Life Sciences, 2021 - Elsevier
Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

Enhancement of therapeutic potential of mesenchymal stem cell-derived extracellular vesicles

KS Park, E Bandeira, GV Shelke, C Lässer… - Stem cell research & …, 2019 - Springer
After the initial investigations into applications of mesenchymal stem cells (MSCs) for cell
therapy, there was increased interest in their secreted soluble factors. Following studies of …

Double‐edged sword of mesenchymal stem cells: cancer‐promoting versus therapeutic potential

HY Lee, IS Hong - Cancer science, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) derived from adipose tissue, bone marrow, cord blood, and
other tissues, have recently attracted much attention as potential therapeutic agents in …

Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer

J Plava, M Cihova, M Burikova, M Matuskova… - Molecular cancer, 2019 - Springer
Although solid tumors comprise malignant cells, they also contain many different non-
malignant cell types in their micro-environment. The cellular components of the tumor stroma …

Genetic stability of mesenchymal stromal cells for regenerative medicine applications: a fundamental biosafety aspect

S Neri - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …

The multifaceted role of mesenchymal stem cells in cancer

M Timaner, KK Tsai, Y Shaked - Seminars in cancer biology, 2020 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stem cells derived from the mesoderm that
give rise to several mesenchymal lineages, including osteoblasts, adipocytes, chondrocytes …

Interaction of MSC with tumor cells

C Melzer, Y Yang, R Hass - Cell Communication and Signaling, 2016 - Springer
Tumor development and tumor progression is not only determined by the corresponding
tumor cells but also by the tumor microenvironment. This includes an orchestrated network …