Cardiovascular disease in diabetes mellitus type 2: a potential role for novel cardiovascular risk factors

JM Hayden, PD Reaven - Current opinion in lipidology, 2000 - journals.lww.com
A major consequence of diabetes mellitus type 2 is the accelerated development of
atherosclerosis. Assessment of conventional risk factors such as plasma lipids, lipoproteins …

The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells

CI Seye, N Yu, R Jain, Q Kong, T Minor… - Journal of biological …, 2003 - ASBMB
P2Y 2 receptor up-regulation and activation induces intimal hyperplasia and monocyte/
macrophage infiltration in the collared rabbit carotid artery model of vascular injury …

Effects of estrogen on the vascular wall: vasomotor function and inflammation

KK Koh - Cardiovascular research, 2002 - academic.oup.com
1. Introduction ly diseased arteries and coronary mortality may not just be related to the
number of arteries with 70% or greater Far from being only an anatomic barrier to prevent …

Pathophysiology and medical treatment of carotid artery stenosis

K Prasad - International Journal of Angiology, 2015 - thieme-connect.com
Stroke is the third leading cause of mortality. Approximately 80 to 85% strokes are ischemic
due to carotid artery stenosis (CAS). The prevalence of significant CAS is 7% in women and …

PPARγ agonists ameliorate endothelial cell activation via inhibition of diacylglycerol–protein kinase C signaling pathway: role of diacylglycerol kinase

E Verrier, L Wang, C Wadham, N Albanese… - Circulation …, 2004 - Am Heart Assoc
Subject—Peroxisome proliferator-activated receptor (PPAR)-γ agonists are emerging as
potential protectors against inflammatory cardiovascular diseases including atherosclerosis …

Adhesion molecules in cerebrovascular diseases: evidence for an inflammatory endothelial activation in cerebral large-and small-vessel disease

K Fassbender, T Bertsch, O Mielke, F Mühlhauser… - Stroke, 1999 - Am Heart Assoc
Background and Purpose—Adhesion molecules mediate attachment and transendothelial
migration of leukocytes as a critical step in pathogenesis of atherosclerosis. Their …

NADPH oxidase activation increases the sensitivity of intracellular Ca2+ stores to inositol 1, 4, 5-trisphosphate in human endothelial cells

Q Hu, G Zheng, JL Zweier, S Deshpande, K Irani… - Journal of Biological …, 2000 - ASBMB
Many stimuli that activate the vascular NADPH oxidase generate reactive oxygen species
and increase intracellular Ca 2+, but whether NADPH oxidase activation directly affects Ca …

Effect of alcohol on lipids and lipoproteins in relation to atherosclerosis

ML Hannuksela, MK Liisanantti… - Critical reviews in …, 2002 - Taylor & Francis
Several studies indicate that light-to-moderate alcohol consumption is associated with a low
prevalence of coronary heart disease. An increase in high-density lipoprotein (HDL) …

Postprandial triglycerides and endothelial function

A Jagla, J Schrezenmeir - Experimental and Clinical …, 2001 - thieme-connect.com
Several studies support the association between postprandially elevated triglyceride levels
and atherosclerosis. Histological and cell culture investigations revealed, that triglyceride …

Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall

C Rodríguez, B Raposo… - … , and vascular biology, 2002 - Am Heart Assoc
Objective—Hypercholesterolemia induces endothelial dysfunction, a hallmark of the
atherosclerotic process, modulating the expression of key genes in vascular endothelial …