LDL Downregulates CYP51 in Porcine Vascular Endothelial Cells and in the Arterial Wall Through a Sterol Regulatory Element Binding Protein-2–Dependent …

C Rodríguez, J Martínez-González… - Circulation …, 2001 - Am Heart Assoc
Hypercholesterolemia is associated with endothelial dysfunction and atherosclerotic lesion
formation. By mRNA–differential display analysis, we have identified lanosterol 14α …

Adenovirus-mediated overexpression of dominant-negative mutant of c-Jun prevents intercellular adhesion molecule-1 induction by LDL: a critical role for activator …

N Wang, L Verna, H Liao, A Ballard, Y Zhu… - … , and vascular biology, 2001 - Am Heart Assoc
Low density lipoprotein (LDL) induces intercellular adhesion molecule-1 (ICAM-1) gene
expression and leads to endothelial cell (EC) leukocyte adhesion. However, the …

Native LDL and Oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-κB, CRE dependent pathway and affect PGE2 synthesis

GD Norata, A Pirillo, F Pellegatta… - International …, 2004 - spandidos-publications.com
Native low density lipoproteins (n-LDL) and oxidized low density lipoproteins (Ox-LDL) play
a central role in atherogenesis and possess a wide variety of biological properties. We …

Modulation of ERG25 expression by LDL in vascular cells

C Rodriguez, B Raposo… - Cardiovascular …, 2003 - academic.oup.com
Background: Plasma low density lipoproteins (LDL) play a key role in the pathogenesis of
atherosclerosis. LDL modify gene expression in vascular cells leading to disturbances in the …

Transplant atherosclerosis: role of phenotypic modulation of vascular smooth muscle by nitric oxide

RE Bundy, N Marczin, EF Birks, AH Chester… - … : The Vascular System, 2000 - Elsevier
Occlusive accelerated atherosclerosis of coronary grafts is the predominant factor that limits
longevity of heart transplant recipients. This form of vascular disease affects both the large …

Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle

M Burnatowska-Hledin, A Zeneberg, A Roulo… - Endothelium, 2001 - Taylor & Francis
The vasopressin-activated calcium-mobilizing (VACM-1) protein is a unique arginine
vasopressin (AVP) receptor which shares sequence homology with the cullins, genes …

Vascular endothelial growth factor gene transfer inhibits neointimal macrophage accumulation in hypercholesterolemic rabbits

R Khurana, S Shafi, J Martin… - … , thrombosis, and vascular …, 2004 - Am Heart Assoc
Objective—This study aims to determine the effects of periadventitial vascular endothelial
growth factor (VEGF) gene transfer on neointima formation and macrophage accumulation …

Examination of adhesion molecules, homocysteine and hs-CRP in patients with polygenic hypercholesterolemia and isolated hypertriglyceridemia

M Calan, O Calan, MS Gonen, F Bilgir… - Internal …, 2011 - jstage.jst.go.jp
Background Increased levels of selectins, adhesion molecules, hs-CRP and homocysteine
are considered important as indicators of atherosclerosis. There is a significant amount of …

In Vitro Functional Testing of Endothelial Progenitor Cells That Overexpress Thrombomodulin

JD Stroncek, Y Xue, N Haque, JH Lawson… - … Engineering Part A, 2011 - liebertpub.com
This study investigated the augmentation of endothelial progenitor cell (EPC)
thromboresistance by using gene therapy to overexpress thrombomodulin (TM), an …

[HTML][HTML] Oxidized LDL further enhances expression of adhesion molecules in Chlamydophila pneumoniae-infected endothelial cells

SA Vielma, M Mironova, JR Ku, MF Lopes-Virella - Journal of lipid research, 2004 - ASBMB
Chlamydophila pneumoniae is a common respiratory pathogen that has been shown to be
associated with coronary artery disease. Recent studies have shown that one of the possible …