Therapeutic antibodies: A new era in the treatment of respiratory diseases?

T Sécher, L Guilleminault, K Reckamp… - Pharmacology & …, 2018 - Elsevier
Respiratory diseases affect millions of people worldwide, and account for significant levels
of disability and mortality. The treatment of lung cancer and asthma with therapeutic …

[HTML][HTML] The emerging role of IL-23 in asthma and its clinical implications

AY Wu, RS Peebles - Expert Review of Clinical Immunology, 2023 - Taylor & Francis
Asthma is a prevalent, chronic inflammatory respiratory disease defined by airway
hyperresponsiveness (AHR), aberrant mucus production, and airway smooth muscle …

[HTML][HTML] Role of interleukin-23 in the development of nonallergic eosinophilic inflammation in a murine model of asthma

HS Lee, DE Park, JW Lee, KH Sohn, SH Cho… - … & Molecular Medicine, 2020 - nature.com
Nonallergic eosinophilic asthma (NAEA) is a clinically distinct subtype of asthma. Thus far,
the pathophysiologic mechanisms underlying NAEA have not been fully elucidated. This …

[HTML][HTML] Decrease of il-5 production by naive t cells cocultured with il-18-producing bcg-pulsed dendritic cells from patients allergic to house dust mite

M Kowalewicz-Kulbat, P Szpakowski, KT Krawczyk… - Vaccines, 2021 - mdpi.com
The only currently available anti-tuberculosis vaccine, Bacillus Calmette–Guérin (BCG), has
been reported to also protect against unrelated diseases, including inflammatory diseases …

[HTML][HTML] Dasatinib attenuates airway inflammation of asthma exacerbation in mice induced by house dust mites and dsRNA

Y Nishimoto, D Ando, K Irie, I Kainuma… - … and Biophysics Reports, 2023 - Elsevier
Asthma exacerbation is a significant clinical problem that causes resistance to corticosteroid
therapy and elevated hospitalization risk. Src family kinases (SFKs) contribute to various …

奥马珠单抗对过敏性哮喘患者血清细胞因子谱的影响

郑晓燕, 孙璘, 汤葳 - 内科理论与实践, 2023 - qk.sjtu.edu.cn
目的: 探讨奥马珠单抗对过敏性哮喘患者血清细胞因子谱的影响. 方法: 纳入2019 年1 月至2021
年1 月在上海交通大学医学院附属瑞金医院呼吸与危重症医学科就诊并接受奥马珠单抗治疗的 …

[PDF][PDF] Decrease of IL-5 Production by Naive T Cells Cocultured with IL-18-Producing BCG-Pulsed Dendritic Cells from Patients Allergic to House Dust Mite. Vaccines …

M Kowalewicz-Kulbat, P Szpakowski, KT Krawczyk… - 2021 - academia.edu
The only currently available anti-tuberculosis vaccine, Bacillus Calmette–Guérin (BCG), has
been reported to also protect against unrelated diseases, including inflammatory diseases …

Expression und Ko-lokalisation von IL-23, IL-23-Rezeptoren und IL-17 auf Makrophagen, Dendritischen Zellen und T-Zellen der Lunge sowie deren potenzielle …

M Leitner - 2022 - publikationen.sulb.uni-saarland.de
Einleitung: Bei Asthma bronchiale handelt es sich um eine variable, reversible Verengung
der Atemwege, ausgelöst durch entzündliche Prozesse innerhalb der Lunge. Das …

Effect of omalizumab treatment on serum cytokine profile in allergic asthma patients

Z Xiaoyan, SUN Lin, T Wei - Journal of Internal Medicine Concepts & …, 2023 - qk.sjtu.edu.cn
Objective To investigate the effect of omalizumab on serum cytokine profile in the patients
with allergic asthma. Methods A total of 20 patients with allergic asthma who received …

[PDF][PDF] Plasma protein biomarkers of ALI and ARDS

S Chen, C Yang, L Zhu, J Jiang - Intern Clin Exp Med, 2017 - e-century.us
Proteomics provides abundant information on the relationships between biological
molecules and disease mechanisms. We selected 507 signaling proteins in the bloodstream …