Nootropic and anti-Alzheimer's actions of medicinal plants: molecular insight into therapeutic potential to alleviate Alzheimer's neuropathology
MS Uddin, A Al Mamun, MT Kabir, M Jakaria… - Molecular …, 2019 - Springer
Medicinal plants are the backbone of modern medicine. In recent times, there is a great urge
to discover nootropic medicinal plants to reverse cognitive dysfunction owing to their less …
to discover nootropic medicinal plants to reverse cognitive dysfunction owing to their less …
Chemistry, biosynthesis and pharmacology of sarsasapogenin: a potential natural steroid molecule for new drug design, development and therapy
Sarsasapogenin is a natural steroidal sapogenin molecule obtained mainly from
Anemarrhena asphodeloides Bunge. Among the various phytosteroids present …
Anemarrhena asphodeloides Bunge. Among the various phytosteroids present …
The genus Anemarrhena Bunge: a review on ethnopharmacology, phytochemistry and pharmacology
Y Wang, Y Dan, D Yang, Y Hu, L Zhang… - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance Anemarrhena asphodeloides
Bunge.(Asparagaceae) yields Anemarrhenae Rhizoma, which has a long history to be used …
Bunge.(Asparagaceae) yields Anemarrhenae Rhizoma, which has a long history to be used …
Toxin-induced experimental models of learning and memory impairment
Animal models for learning and memory have significantly contributed to novel strategies for
drug development and hence are an imperative part in the assessment of therapeutics …
drug development and hence are an imperative part in the assessment of therapeutics …
Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease. There are a limited number of
therapeutic options available for the treatment of AD. Curcuminoids (a mixture of …
therapeutic options available for the treatment of AD. Curcuminoids (a mixture of …
Sarsasapogenin restores podocyte autophagy in diabetic nephropathy by targeting GSK3β signaling pathway
X Li, H Jiang, L Xu, YQ Liu, J Tang, JS Shi, X Yu… - Biochemical …, 2021 - Elsevier
Podocyte injury following abnormal podocyte autophagy plays an indispensable role in
diabetic nephropathy (DN), therefore, restoration of podocyte autophagy is considered as a …
diabetic nephropathy (DN), therefore, restoration of podocyte autophagy is considered as a …
Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice
B Lee, K Jung, DH Kim - Pharmacology Biochemistry and Behavior, 2009 - Elsevier
Anemarrhenaasphodeloides Bunge (AA, family Liliaceae), which primarily contains
xantones, such as mangiferin, and steroidal saponins, such as timosaponin AIII and …
xantones, such as mangiferin, and steroidal saponins, such as timosaponin AIII and …
Timosaponin AIII induces G2/M arrest and apoptosis in breast cancer by activating the ATM/Chk2 and p38 MAPK signaling pathways
M Zhang, J Qu, Z Gao, Q Qi, H Yin, L Zhu… - Frontiers in …, 2021 - frontiersin.org
Timosaponin AIII (TAIII), a steroidal saponin, exerts potent anti-tumor activity in various
cancers, especially breast cancer. However, the concrete molecular mechanisms of TAIII …
cancers, especially breast cancer. However, the concrete molecular mechanisms of TAIII …
Anti-amnesic effect of pseudoginsenoside-F11 in two mouse models of Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
amyloid β (Aβ) deposits, elevated oxidative stress, and apoptosis of the neurons …
amyloid β (Aβ) deposits, elevated oxidative stress, and apoptosis of the neurons …
The treatment of Alzheimer's disease using Chinese medicinal plants: from disease models to potential clinical applications
Y Su, Q Wang, C Wang, K Chan, Y Sun… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance Alzheimer's disease (AD) is characterized by the
sustained higher nervous disorders of the activities and functions of the brain. Due to its …
sustained higher nervous disorders of the activities and functions of the brain. Due to its …