Galectins are carbohydrate-binding proteins that are involved in many physiological
functions, such as inflammation, immune responses, cell migration, autophagy and …

Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

Sialic acid sugar-carrying glycans, sialoglycans, are aberrantly expressed on many tumor
cells and have emerged as potent regulatory molecules involved in creating a tumor …

It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast
number of biological processes through intercellular transfer of biomolecules. Increasing …

The wide occurrence of sialic acids (Sia) in various chemical forms linked as monomers or
polymers in an outstanding position in a multitude of complex carbohydrates of animals and …

Most cell surface proteins are decorated by glycans, and the plasma membrane is rich in
glycosylated lipids. The mechanisms by which the enormous complexity of these glycan …

Abstract Background Galectins are β-Galactose binding lectins expressed in numerous cells
and play multiple roles in various physiological and cellular functions. However, few …

We have explored the fundamental biological processes by which complex carbohydrates
expressed on cellular glycoproteins and glycolipids and in secretions of cells promote cell …

Glycoproteins are major players in the mucus protective barrier in the gastrointestinal and
other mucosal surfaces. In particular the mucus glycoproteins, or mucins, are responsible for …

During oncogenesis, tumor cells present specific carbohydrate chains that are new targets
for cancer immunotherapy. Whereas these tumor-associated carbohydrates (TACA) can be …