Apolipoprotein A1‐related proteins and reverse cholesterol transport in antiatherosclerosis therapy: Recent progress and future perspectives

X Xu, Z Song, B Mao, G Xu - Cardiovascular Therapeutics, 2022 - Wiley Online Library
Hyperlipidemia characterized by abnormal deposition of cholesterol in arteries can cause
atherosclerosis and coronary artery occlusion, leading to atherosclerotic coronary heart …

SR-B1, a key receptor involved in the progression of cardiovascular disease: a perspective from mice and human genetic studies

I Gracia-Rubio, C Martín, F Civeira, A Cenarro - Biomedicines, 2021 - mdpi.com
High plasma level of low-density lipoprotein (LDL) is the main driver of the initiation and
progression of cardiovascular disease (CVD). Nevertheless, high-density lipoprotein (HDL) …

The effect of cinnamon supplementation on lipid profiles in patients with type 2 diabetes: A systematic review and meta-analysis of clinical trials

N Jamali, A Kazemi, J Saffari-Chaleshtori… - … Therapies in Medicine, 2020 - Elsevier
Objective The present systematic review and meta-analysis was performed to evaluate the
effect of cinnamon supplementation on blood lipid profiles in patients with type 2 diabetes …

The SNPs rs429358 and rs7412 of APOE gene are association with cerebral infarction but not SNPs rs2306283 and rs4149056 of SLCO1B1 gene in southern …

H Wu, Q Huang, Z Yu, H Wu, Z Zhong - Lipids in Health and Disease, 2020 - Springer
Abstract Background Apolipoprotein E (ApoE) and solute carrier organic anion transporter
family member 1B1 (SLCO1B1) regulate lipid metabolism. However, the relationship …

High‐density lipoprotein‐related cholesterol metabolism in Alzheimer's disease

S Pedrini, P Chatterjee, E Hone… - Journal of …, 2021 - Wiley Online Library
High‐density lipoproteins (HDL) are a heterogeneous class of molecules whose main
function is to remove excess cholesterol through a mechanism called reverse transport, in …

Platelet endothelial aggregation receptor 1 polymorphism is associated with functional outcome in small-artery occlusion stroke patients treated with aspirin

Z Li, H Jiang, Y Ding, D Zhang, X Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: The role of genetic polymorphisms is important in defining the patient's
prognosis and outcomes in coronary artery disease. The present study aimed to explore the …

Scavenger receptor Class B type I as a potential risk stratification biomarker and therapeutic target in cardiovascular disease

R Sahebi, SM Hassanian… - Journal of Cellular …, 2019 - Wiley Online Library
Cardiovascular disease (CVD) is the leading cause of mortality globally. There are few
useful markers available for CVD risk stratification that has proven clinical utility. Scavenger …

SCARB1 rs5888 gene polymorphisms in coronary heart disease: a systematic review and a meta-analysis

R Ma, X Zhu, B Yan - Gene, 2018 - Elsevier
Background Studies have suggested that high-density lipoprotein (HDL) stimulates
scavenger receptor class B type 1 (SR-B1) to promote hepatic uptake of cholesterol. SR-B1 …

[PDF][PDF] Investigation of Scavenger Receptor Class B Type I gene variants in patients with coronary heart disease with a history of early myocardial infarction.

B Çaykara, B Tokat, E Coşkunpınar… - Archives of the …, 2021 - jag.journalagent.com
Objective: The scavenger receptor class B type 1 (SR-BI, SCARB1), which is a high-density
lipoprotein (HDL) receptor that mediates selective cholesteryl ester uptake, plays an …

Rare P376L variant in the SR-BI gene associates with HDL dysfunction and risk of cardiovascular disease

S Samadi, Z Farjami, ZS Hosseini, GA Ferns… - Clinical …, 2019 - Elsevier
Background Scavenger receptor class B type 1 (SR-BI) encoded by SCARB1 gene serves
as a multifunctional HDL receptor, facilitating the uptake of cholesteryl esters from HDL to …