Kaempferol: A flavonoid with wider biological activities and its applications

SP Bangar, V Chaudhary, N Sharma… - Critical Reviews in …, 2023 - Taylor & Francis
Kaempferol and its derivatives are naturally occurring phytochemicals with promising
bioactivities. This flavonol can reduce the lipid oxidation in the human body, prevent the …

[HTML][HTML] Cancer chemoprevention: A strategic approach using phytochemicals

M Swetha, CK Keerthana, TP Rayginia… - Frontiers in …, 2022 - frontiersin.org
Cancer chemoprevention approaches are aimed at preventing, delaying, or suppressing
tumor incidence using synthetic or natural bioactive agents. Mechanistically …

[HTML][HTML] Flavonoids: Their putative neurologic roles, epigenetic changes, and gut microbiota alterations in Parkinson's disease

Y Açar, D Ağagündüz, P De Cicco… - Biomedicine & …, 2023 - Elsevier
Abstract Parkinson's Disease (PD), a neurodegenerative disorder, is characterized by the
degeneration of progressive dopaminergic (DA) neurons in the substantia nigra region of …

[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury

Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

The natural (poly) phenols as modulators of microglia polarization via TLR4/NF-κB pathway exert anti-inflammatory activity in ischemic stroke

R Li, Y Zhou, S Zhang, J Li, Y Zheng, X Fan - European journal of …, 2022 - Elsevier
Increasing evidences suggest that inflammation plays a key role in the pathogenesis of
stroke, a devastating disease second only to cardiac ischemia as a cause of death …

[HTML][HTML] Antioxidant role of kaempferol in prevention of hepatocellular carcinoma

N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …

[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components

K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

The most potent natural pharmaceuticals, cosmetics, and food ingredients isolated from plants with deep eutectic solvents

A Wawoczny, D Gillner - Journal of Agricultural and Food …, 2023 - ACS Publications
There is growing interest in reducing the number of synthetic products or additives and
replacing them with natural ones. The pharmaceutical, cosmetic, and food industries are …

Flavonoids as promising neuroprotectants and their therapeutic potential against Alzheimer's disease

T Minocha, H Birla, AA Obaid, V Rai… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …

[HTML][HTML] Neuroprotective effect of artichoke-based nanoformulation in sporadic Alzheimer's disease mouse model: focus on antioxidant, anti-inflammatory, and …

HAS El-Nashar, H Abbas, M Zewail, MH Noureldin… - Pharmaceuticals, 2022 - mdpi.com
The vast socio-economic impact of Alzheimer's disease (AD) has prompted the search for
new neuroprotective agents with good tolerability and safety profile. With its outstanding role …