Complexes of ruthenium (II) as promising dual-active agents against cancer and viral infections
Poor responses to medical care and the failure of pharmacological treatment for many high-
frequency diseases, such as cancer and viral infections, have been widely documented. In …
frequency diseases, such as cancer and viral infections, have been widely documented. In …
Revolutionizing anticancer treatment: Ruthenium-based nanoplatforms pave new paths
Cancer ranks among the top causes of mortality on a global scale. The only treatments
available for cancer nowadays are surgery, radiation therapy, and the use of cytotoxic …
available for cancer nowadays are surgery, radiation therapy, and the use of cytotoxic …
Neoadjuvant hyperthermia combined with hybrid nanoarchitectures enhances chemoradiotherapy efficacy in head and neck carcinoma
P Sarogni, V Frusca, A Zamborlin… - … Applied Materials & …, 2024 - ACS Publications
Head and neck squamous cell carcinomas are characterized by a high incidence of
recurrence, especially in patients with locally advanced disease. Standard treatment …
recurrence, especially in patients with locally advanced disease. Standard treatment …
Drug-Free Hybrid Nanoarchitecture Modulation of the Metastatic Behavior of Pancreatic Ductal Adenocarcinoma in Alternative in Vivo Models
A Zamborlin, P Sarogni, V Frusca… - ACS Applied Nano …, 2023 - ACS Publications
Metastasis is the key cause of treatment failure in most oncological patients. The spreading
of cancer cells to distal tissues and organs can be associated with the epithelial-to …
of cancer cells to distal tissues and organs can be associated with the epithelial-to …
[HTML][HTML] Organic Selenium induces ferroptosis in pancreatic cancer cells
R Noe, N Inglese, P Romani, T Serafini, C Paoli… - Redox Biology, 2023 - Elsevier
Pancreatic ductal adenocarcinoma (PDA) cells reprogram both mitochondrial and lysosomal
functions to support growth. At the same time, this causes significant dishomeostasis of free …
functions to support growth. At the same time, this causes significant dishomeostasis of free …
Evolving approaches in glioma treatment: harnessing the potential of copper metabolism modulation
The key properties and high versatility of metal nanoparticles have shed new perspectives
on cancer therapy, with copper nanoparticles gaining great interest because of the ability to …
on cancer therapy, with copper nanoparticles gaining great interest because of the ability to …
Metallic nanoparticles unveiled: Synthesis, characterization, and their environmental, medicinal, and agricultural applications
Metallic nanoparticles (MNPs) have attracted great interest among scientists and
researchers for years due to their unique optical, physiochemical, biological, and magnetic …
researchers for years due to their unique optical, physiochemical, biological, and magnetic …
Tumor growth-arrest effect of tetrahydroquinazoline-derivative human topoisomerase II-alpha inhibitor in HPV-negative head and neck squamous cell carcinoma
P Sarogni, N Brindani, A Zamborlin, A Gonnelli… - Scientific Reports, 2024 - nature.com
Oral malignancies continue to have severe morbidity with less than 50% long-term survival
despite the advancement in the available therapies. There is a persisting demand for new …
despite the advancement in the available therapies. There is a persisting demand for new …
Copper nano-architecture topical cream for the accelerated recovery of burnt skin
Skin burns are debilitating injuries with significant morbidity and mortality associated with
infections and sepsis, particularly in immunocompromised patients. In this context …
infections and sepsis, particularly in immunocompromised patients. In this context …
[HTML][HTML] Invasiveness modulation of glioma cells by copper complex-loaded nanoarchitectures
Among the tumors with the highest lethality, gliomas are primary brain tumors associated
with common recurrence inclined to metastasize along the neuraxis and occasionally out of …
with common recurrence inclined to metastasize along the neuraxis and occasionally out of …