Recent studies demonstrate that histones are subjected to a series of short-chain fatty acid
modifications that is known as histone acylations. However, the enzymes responsible for …

While the epithelial-mesenchymal transition (EMT) plays a fundamental role during
development, its deregulation can adversely promote tumor metastasis. The phenotypic and …

Brain Derived Neurotrophic Factor (BDNF) is a unique member of the neurotrophin family
with potent and plethoric effects on the proliferation, differentiation, survival and death of …

Breast cancer (BC) cell de-sensitization to Tamoxifen (TAM) or other selective estrogen
receptor (ER) modulators (SERM) is a complex process associated with BC heterogeneity …

Global alterations in epigenetic landscape are now recognized as a hallmark of cancer.
Epigenetic mechanisms such as DNA methylation, histone modifications, nucleosome …

Histone methylations are important chromatin marks that regulate gene expression, genomic
stability, DNA repair, and genomic imprinting. Histone demethylases are the most recent …

Inflammatory bowel diseases (IBDs) are characterized by inflammation in the
gastrointestinal tract and include Ulcerative Colitis and Crohn's Disease. These diseases …

Epigenetics, an inheritable phenomenon, which influences the expression of gene without
altering the DNA sequence, offers a new perspective on the pathogenesis of hepatocellular …

Diabetes activates retinal matrix metalloproteinase-9 (MMP-9), and MMP-9 damages the
mitochondria and augments capillary cell apoptosis. Our aim is to elucidate the mechanism …

Laboratory experiments and fieldwork with asexually reproducing invertebrates and
vertebrates clearly revealed that animal populations can produce substantial phenotypic …