The epithelial-to-mesenchymal transition (EMT) is a process by which differentiated
epithelial cells reprogram gene expression, lose their junctions and polarity, reorganize their …

Jumonji C (JmjC) domain-containing proteins are a diverse superfamily of proteins
containing a characteristic, evolutionarily conserved β-barrel structure that normally contains …

The MYST protein lysine acetyltransferases are evolutionarily conserved throughout
eukaryotes and acetylate proteins to regulate diverse biological processes including gene …

Histone deacetylase inhibitors (HDACi) are in clinical trials against a variety of cancers.
Despite early successes, results against the more common solid tumors have been mixed …

Epigenomics is a rapidly growing field. New developments in epigenetics, such as the
recently described modified cytosine variants (eg, 5‐hydroxymethylcytosine, 5hmC) and an …

The concept of epigenetics has been known about since the 1940s, but it is only in the last
10 years that research has shown just how wide ranging its effects are. It is now a very …

The emergence of drug-resistant fungi poses a continuously increasing threat to human
health. Despite advances in preventive care and diagnostics, resistant fungi continue to …

Spermatozoa (SPZ) are motile cells, characterized by a cargo of epigenetic information
including histone post-translational modifications (histone PTMs) and non-coding RNAs …

Diabetes mellitus is a worldwide health problem that usually comes with severe
complications. There is no cure for diabetes yet and the threat of these complications is what …

Gene–environment interactions have long been recognized for their important role in
mediating the development and functions of the central nervous system (CNS). The study of …