Background The genome-wide hyperacetylation of chromatin caused by histone
deacetylase inhibitors (HDACi) is surprisingly well tolerated by most eukaryotic cells. The …

Background Climate change has had a tremendous impact on the environment in general
as well as agricultural crops grown in these situations as time passed. Agricultural …

Lysine methylation has emerged as a prominent covalent modification in histones and non-
histone proteins. This modification has been implicated in numerous genomic processes …

Adverse events in utero can be critical in determining quality of life and overall health. It is
estimated that up to 50% of metabolic syndrome diseases can be linked to an adverse fetal …

The general transcription factor IID (TFIID) initiates RNA polymerase II-mediated eukaryotic
transcription by nucleating pre-initiation complex formation at the core promoter of protein …

Stress in early life has been appointed as an important phenomenon in the onset of
depression and poor response to treatment with classical antidepressants. Furthermore …

Abstract Suppressor of variegation 3–9 homolog 2 (SUV39H2) is a member of the SUV39H
subfamily of lysine methyltransferases. Its role in colorectal cancer (CRC) proliferation and …

Histone deacetylases (HDACs) are enzymes that cleave acetyl groups from acetyl-lysine
residues in histones and various nonhistone proteins. Unlike the other three of the four …

Despite many advances in treatment over the past few years, the poor 5-year survival rate
and high recurrence rate of gastric cancer (GC) remain unsatisfactory. As the most abundant …

In addition to traditional drugs, such as enzyme inhibitors, receptor agonists/antagonists,
and protein‐protein interaction inhibitors as well as genetic technology, such as RNA …