Scaling and systems biology for integrating multiple organs-on-a-chip
Coupled systems of in vitro microfabricated organs-on-a-chip containing small populations
of human cells are being developed to address the formidable pharmacological and …
of human cells are being developed to address the formidable pharmacological and …
Applications for preclinical PET/MRI
MS Judenhofer, SR Cherry - Seminars in nuclear medicine, 2013 - Elsevier
Currently, the combination of positron emission tomography (PET) and magnetic resonance
imaging (MRI) as a hybrid imaging modality is receiving great attention not only in its …
imaging (MRI) as a hybrid imaging modality is receiving great attention not only in its …
Small-animal molecular imaging methods
RA De Kemp, FH Epstein, C Catana… - Journal of Nuclear …, 2010 - Soc Nuclear Med
The ability to trace or identify specific molecules within a specific anatomic location provides
insight into metabolic pathways, tissue components, and tracing of solute transport …
insight into metabolic pathways, tissue components, and tracing of solute transport …
In vivo labeling of serum albumin for PET
G Niu, L Lang, DO Kiesewetter, Y Ma… - Journal of Nuclear …, 2014 - Soc Nuclear Med
The purpose of this study was to develop a novel in vivo albumin-labeling method to allow
PET of cardiac function after myocardial infarction and vascular leakage and increased …
PET of cardiac function after myocardial infarction and vascular leakage and increased …
Measuring right ventricular function in the normal and hypertensive mouse hearts using admittance-derived pressure-volume loops
DM Tabima, TA Hacker… - American Journal of …, 2010 - journals.physiology.org
Mice are a widely used animal model for investigating cardiovascular disease. Novel
technologies have been used to quantify left ventricular function in this species, but …
technologies have been used to quantify left ventricular function in this species, but …
Recent advances in cardiovascular diseases research using animal models and PET radioisotope tracers
W Wargocka-Matuszewska, W Uhrynowski… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVD) is a collective term describing a range of conditions that
affect the heart and blood vessels. Due to the varied nature of the disorders, distinguishing …
affect the heart and blood vessels. Due to the varied nature of the disorders, distinguishing …
Molecular magnetic resonance imaging of myocardial angiogenesis after acute myocardial infarction
M Oostendorp, K Douma, A Wagenaar, JMGM Slenter… - Circulation, 2010 - Am Heart Assoc
Background—Angiogenesis is a natural mechanism to restore perfusion to the ischemic
myocardium after acute myocardial infarction (MI). Therapeutic angiogenesis is being …
myocardium after acute myocardial infarction (MI). Therapeutic angiogenesis is being …
Determination of three‐dimensional ventricular strain distributions in gene‐targeted mice using tagged MRI
JS Chuang, A Zemljic‐Harpf, RS Ross… - Magnetic resonance …, 2010 - Wiley Online Library
A model‐based method for calculating three‐dimensional (3D) cardiac wall strain
distributions in the mouse has been developed and tested in a genetically engineered …
distributions in the mouse has been developed and tested in a genetically engineered …
Small animal cardiovascular MR imaging and spectroscopy
AJ Bakermans, D Abdurrachim, RPM Moonen… - Progress in nuclear …, 2015 - Elsevier
The use of MR imaging and spectroscopy for studying cardiovascular disease processes in
small animals has increased tremendously over the past decade. This is the result of the …
small animals has increased tremendously over the past decade. This is the result of the …
Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI
K Büscher, MS Judenhofer, MT Kuhlmann… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Recently, integrated small-animal PET/MRI prototypes that provide isochronous and
coregistered datasets of morphology and function through the simultaneous acquisition of …
coregistered datasets of morphology and function through the simultaneous acquisition of …