The aetiology and molecular landscape of insulin resistance
Insulin resistance, defined as a defect in insulin-mediated control of glucose metabolism in
tissues—prominently in muscle, fat and liver—is one of the earliest manifestations of a …
tissues—prominently in muscle, fat and liver—is one of the earliest manifestations of a …
Mechanisms of muscle insulin resistance and the cross‐talk with liver and adipose tissue
SC da Silva Rosa, N Nayak, AM Caymo… - Physiological …, 2020 - Wiley Online Library
Insulin resistance is a metabolic disorder affecting multiple tissues and is a precursor event
to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an …
to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an …
Mechanisms of estrogen influence on skeletal muscle: mass, regeneration, and mitochondrial function
A Pellegrino, PM Tiidus, R Vandenboom - Sports medicine, 2022 - Springer
Human menopause is widely associated with impaired skeletal muscle quality and
significant metabolic dysfunction. These observations pose significant challenges to the …
significant metabolic dysfunction. These observations pose significant challenges to the …
Targeting PI3K-AKT/mTOR signaling in the prevention of autism
A Sharma, S Mehan - Neurochemistry international, 2021 - Elsevier
Abstract PI3K-AKT/mTOR signaling pathway represents an essential signaling mechanism
for mammalian enzyme-related receptors in transducing signals or biological processes …
for mammalian enzyme-related receptors in transducing signals or biological processes …
Benefits and risks associated with meat consumption during key life processes and in relation to the risk of chronic diseases
C Giromini, DI Givens - Foods, 2022 - mdpi.com
Red meat has been an important part of the diet throughout human evolution. Overall, when
included as part of a healthy and varied diet, red meat can provide a rich source of …
included as part of a healthy and varied diet, red meat can provide a rich source of …
[HTML][HTML] Physiology, glucose metabolism
MN Nakrani, RH Wineland, F Anjum - 2020 - europepmc.org
Glucose is central to energy consumption. Carbohydrates, lipids, and proteins all ultimately
break down into glucose, which then serves as the primary metabolic fuel of mammals and …
break down into glucose, which then serves as the primary metabolic fuel of mammals and …
Insulin signalling and GLUT4 trafficking in insulin resistance
J van Gerwen, AS Shun-Shion… - Biochemical Society …, 2023 - portlandpress.com
Insulin-stimulated glucose uptake into muscle and adipose tissue is vital for maintaining
whole-body glucose homeostasis. Insulin promotes glucose uptake into these tissues by …
whole-body glucose homeostasis. Insulin promotes glucose uptake into these tissues by …
Insulin: The master regulator of glucose metabolism
Insulin is the master regulator of glucose, lipid, and protein metabolism. Following ingestion
of an oral glucose load or mixed meal, the plasma glucose concentration rises, insulin …
of an oral glucose load or mixed meal, the plasma glucose concentration rises, insulin …
Ultrasound-assisted deep eutectic solvent extraction of polysaccharides from Anji White tea: Characterization and comparison with the Conventional Method
B Xia, Q Liu, D Sun, Y Wang, W Wang, D Liu - Foods, 2023 - mdpi.com
Deep eutectic solvent as a new green and safe solvent system has attracted more and more
attention in recent years. In this study, three deep eutectic solvents (DES) were combined …
attention in recent years. In this study, three deep eutectic solvents (DES) were combined …
Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling
S Mishra, C Cosentino, AK Tamta, D Khan… - Nature …, 2022 - nature.com
Chronic activation of stress hormones such as glucocorticoids leads to skeletal muscle
wasting in mammals. However, the molecular events that mediate glucocorticoid-induced …
wasting in mammals. However, the molecular events that mediate glucocorticoid-induced …