Simple Summary The high lethality of colorectal cancer (CRC) is anticipated to continue in
the following decades. Early-stage CRC is entirely treatable with surgery and adjuvant …

Abstract Epithelial-mesenchymal transitions (EMTs), the acquisition of mesenchymal
features from epithelial cells, occur during some biological processes and are classified into …

Fluorouracil (5-FU) is an essential component of systemic chemotherapy for colorectal
cancer (CRC) in the palliative and adjuvant settings. Over the past four decades, several …

Yes‐associated protein (YAP) has been identified as a key driver for epidermal growth factor
receptor‐tyrosine kinase inhibitor (EGFR‐TKI) resistance. Inhibition of YAP expression could …

The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

Background: Phosphoinositide 3-kinase (PI3Ks) is a member of intracellular lipid kinases
and involved in the regulation of cellular proliferation, differentiation and survival …

As Allium cepa is one of the most important condiment plants grown and consumed all over
the world, various therapeutic and pharmacological effects of A. cepa were reviewed. Onion …

MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs that can post-
transcriptionally regulate the expression of various oncogenes and tumor suppressor genes …

Background Colorectal cancer (CRC) is one of the most common forms of cancer worldwide.
The tumor microenvironment plays a key role in promoting the occurrence of …

Herein, redox responsive chitosan/stearic acid nanoparticles (CSSA NPs)(≈ 200 nm) are
developed for dual drug delivery. These degradable nanoparticles are prepared based on …