Reactive oxygen species (ROS) and the closely related reactive nitrogen species (RNS) are
often generated in applications of atmospheric pressure plasmas intended for biomedical …

Highlights•A bibliometric review of drug repurposing provides novel insights into the
practice.•Some drugs have been tried in hundreds of diseases.•Even an old drug like …

Chloroquine (CQ), N′-(7-chloroquinolin-4-yl)-N, N-diethyl-pentane-1, 4-diamine, is widely
used as an effective and safe anti-malarial and anti-rheumatoid agent. CQ was discovered …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new viral disease that
has gained global attention owing to its ability to provoke community and health-care …

Despite decades of research, little is known about the cellular targets and the mode of action
of the vast majority of antimalarial drugs. We recently demonstrated that the cellular thermal …

With advances in sequencing technology, uncharacterized proteins and domains of
unknown function (DUFs) are rapidly accumulating in sequence databases and offer an …

Asbestos causes malignant transformation of primary human mesothelial cells (HM), leading
to mesothelioma. The mechanisms of asbestos carcinogenesis remain enigmatic, as …

Thiopeptides, or thiazolyl peptides, are a relatively new family of antibiotics that already
counts with more than one hundred different entities. Although they are mainly isolated from …

Infective diseases have become health threat of a global proportion due to appearance and
spread of microorganisms resistant to majority of therapeutics currently used for their …

The development of multi-resistant strains of plasmodium parasite has become a global
problem, therefore, the discovery of new antimalarial agents is the only available solution. In …