Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal
women worldwide and is characterized by reproductive, endocrine, and metabolic …

An equilibrium needs to be established by the cellular and acellular components of the
ovarian follicle if developmental competence is to be acquired by the oocyte. Both cumulus …

Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …

Mitochondrial function and glucose metabolism play important roles in bidirectional
signaling between granulosa cells (GCs) and oocytes. However, the factors associated with …

As important metabolic substrates, branched-chain amino acids (BCAAs) and fatty acids
(FAs) participate in many significant physiological processes, such as mitochondrial …

Mitochondrial injury in granulosa cells is associated with the pathogenesis of polycystic
ovary syndrome (PCOS). However, the protective effects of melatonin against mitochondrial …

Polycystic ovarian syndrome (PCOS) is one of the leading causes of anovulatory infertility in
women, affecting 5%–15% of women of reproductive age worldwide. The clinical …

Significance: The precipitous age-related decline in female fertility is intimately associated
with a reduction in both the quantity and quality of the germline (oocytes). Although complex …

Iron, as an essential trace element for the organism, is vital for maintaining the organism's
health. Excessive iron can promote reactive oxygen species (ROS) accumulation, thus …

Polycystic ovary syndrome (PCOS) represents one of the leading causes of anovulatory
infertility and affects 5% to 20% of women worldwide. Until today, both the subsequent …