The limitations of current chemotherapeutic drugs are still a major issue in cancer treatment.
Thus, targeted multimodal therapeutic approaches need to be strategically developed to …

Cancer continues to be responsible for the deaths of more than 9 million people worldwide
each year. Current treatment options are diverse, but low success rates, particularly for those …

Metal complexes have shown great potential in cancer immunotherapy. This review briefly
introduces the basic concepts and strategies of cancer immunotherapy and summarizes the …

According to its different occurrence mechanism, programmed cell death (PCD) is divided
into apoptosis, autophagy, necrosis, paraptosis and so on. Paraptosis is morphologically …

Reactive oxygen species (ROS) are rapidly eliminated and reproduced in organisms, and
they always play important roles in various biological functions and abnormal pathological …

A series of Cu (diimine)(X-sal)(NO3) complexes, where the diimine is either 2, 2′-bipyridine
(bpy) or 1, 10-phenanthroline (phen) and X-sal is a monoanionic halogenated …

A series of cyclometalated iridium (III) complexes with the formula [Ir (C^ N) 2 L](PF6)(C^ N=
2-phenylpyridine (ppy, in Ir-1), 2-(2-thienyl) pyridine (thpy, in Ir-2), 2-(2, 4-difluorophenyl) …

Probing the activity of cytochrome P450 3A4 (CYP3A4) is critical for monitoring the
metabolism of pharmaceuticals and identifying drug–drug interactions. A library of Ir (III) …

Cell death can be classified into two primary categories: accidental cell death and regulated
cell death (RCD). Within RCD, there are distinct apoptotic and non-apoptotic cell death …

Luminescent cyclometallated iridium (III) complexes with a polyhedral oligomeric
silsesquioxane (POSS) unit were designed as efficient theranostic agents that displayed …