Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health

WJY Chee, SY Chew, LTL Than - Microbial cell factories, 2020 - Springer
Human vagina is colonised by a diverse array of microorganisms that make up the normal
microbiota and mycobiota. Lactobacillus is the most frequently isolated microorganism from …

[HTML][HTML] The female vaginal microbiome in health and bacterial vaginosis

X Chen, Y Lu, T Chen, R Li - Frontiers in cellular and infection …, 2021 - frontiersin.org
The vaginal microbiome is an intricate and dynamic microecosystem that constantly
undergoes fluctuations during the female menstrual cycle and the woman's entire life. A …

[HTML][HTML] Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease

J Ravel, I Moreno, C Simón - American journal of obstetrics and …, 2021 - Elsevier
Bacterial vaginosis, pelvic inflammatory disease, and endometritis are infections of the
genital tract that can lead to many adverse health outcomes, including infertility. Bacterial …

Advances in understanding the human urinary microbiome and its potential role in urinary tract infection

ML Neugent, NV Hulyalkar, VH Nguyen, PE Zimmern… - MBio, 2020 - Am Soc Microbiol
Recent advances in the analysis of microbial communities colonizing the human body have
identified a resident microbial community in the human urinary tract (UT). Compared to many …

Host–vaginal microbiota interactions in the pathogenesis of bacterial vaginosis

CA Muzny, P Łaniewski, JR Schwebke… - Current opinion in …, 2020 - journals.lww.com
Elucidating the cause of bacterial vaginosis has important implications for diagnosis and
treatment. Our current bacterial vaginosis pathogenesis model provides a framework for key …

Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression

DJ Delgado-Diaz, B Jesaveluk, JA Hayward, D Tyssen… - Microbiome, 2022 - Springer
Background Women with a cervicovaginal microbiota dominated by Lactobacillus spp. are at
reduced risk of acquiring sexually transmitted infections including HIV, but the biological …

The cervicovaginal mucus barrier

G Lacroix, V Gouyer, F Gottrand… - International Journal of …, 2020 - mdpi.com
Preterm births are a global health priority that affects 15 million babies every year worldwide.
There are no effective prognostic and therapeutic strategies relating to preterm delivery, but …

The healthy female microbiome across body sites: effect of hormonal contraceptives and the menstrual cycle

MC Krog, LW Hugerth, E Fransson, Z Bashir… - Human …, 2022 - academic.oup.com
STUDY QUESTION How does hormonal contraceptive use and menstrual cycle phase affect
the female microbiome across different body sites? SUMMARY ANSWER The menstrual …

Distinct immune responses elicited from cervicovaginal epithelial cells by lactic acid and short chain fatty acids associated with optimal and non-optimal vaginal …

DJ Delgado-Diaz, D Tyssen, JA Hayward… - Frontiers in cellular …, 2020 - frontiersin.org
Non-optimal vaginal microbiota, as observed in bacterial vaginosis (BV), is typically
characterized by a depletion of beneficial lactobacilli and an abundance of numerous …

Gardnerella vaginalis alters cervicovaginal epithelial cell function through microbe-specific immune responses

L Anton, B Ferguson, ES Friedman, KD Gerson… - Microbiome, 2022 - Springer
Background The cervicovaginal (CV) microbiome is highly associated with vaginal health
and disease in both pregnant and nonpregnant individuals. An overabundance of …