Uncovering the underworld of axial spondyloarthritis
S Del Vescovo, V Venerito, C Iannone… - International journal of …, 2023 - mdpi.com
Axial spondyloarthritis (axial-SpA) is a multifactorial disease characterized by inflammation
in sacroiliac joints and spine, bone reabsorption, and aberrant bone deposition, which may …
in sacroiliac joints and spine, bone reabsorption, and aberrant bone deposition, which may …
HLA-B* 27 and ankylosing spondylitis: 50 years of insights and discoveries
MA Khan - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review To commemorate the 50th anniversary of the groundbreaking
discovery of a remarkably strong association between HLA-B* 27 and ankylosing spondylitis …
discovery of a remarkably strong association between HLA-B* 27 and ankylosing spondylitis …
EULAR study group on 'MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders
JJW Kuiper, JC Prinz, E Stratikos… - Annals of the …, 2023 - ard.bmj.com
The 'MHC-I (major histocompatibility complex class I)-opathy'concept describes a family of
inflammatory conditions with overlapping clinical manifestations and a strong genetic link to …
inflammatory conditions with overlapping clinical manifestations and a strong genetic link to …
[PDF][PDF] Improving sampling of crystallographic disorder in ensemble refinement
Ensemble refinement, the application of molecular dynamics to crystallographic refinement,
explicitly models the disorder inherent in macromolecular structures. These ensemble …
explicitly models the disorder inherent in macromolecular structures. These ensemble …
The impact of the 'mis-peptidome'on HLA class I-mediated diseases: contribution of ERAP1 and ERAP2 and effects on the immune response
V Tedeschi, G Paldino, F Paladini, B Mattorre… - International Journal of …, 2020 - mdpi.com
The strong association with the Major Histocompatibility Complex (MHC) class I genes
represents a shared trait for a group of autoimmune/autoinflammatory disorders having in …
represents a shared trait for a group of autoimmune/autoinflammatory disorders having in …
Venus flytrap or pas de trois? The dynamics of MHC class I molecules
N Jantz-Naeem, S Springer - Current Opinion in Immunology, 2021 - Elsevier
The peptide binding site of major histocompatibility complex (MHC) class I molecules is
natively unfolded when devoid of peptides. Peptide binding stabilizes the structure and …
natively unfolded when devoid of peptides. Peptide binding stabilizes the structure and …